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Cranio osteoarthropathy

Orpha number ORPHA1525
Prevalence of rare diseases <1 / 1 000 000
Inheritance
  • Autosomal dominant
Age of onset Childhood
ICD 10 code -
MIM number
Synonym(s) Reginato-Schiapachasse syndrome

Summary

Cranio osteoarthropathy syndrome is a rare form of osteoarthropathy seemingly distinct from pachydermoperiostosis. It has been described in only 4 children, 3 of them being sisters. The salient features are clinodactyly of the fingers, eczematous skin eruption, periosteal new bone formation, and defects of the cranial bones resulting in wide fontanelles. It is likely to be inherited as an autosomal recessive trait. *Author: Orphanet (October 2004)*.

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