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Stein-Leventhal syndrome

Orpha number ORPHA3185
Prevalence of rare diseases >1 / 1000
Inheritance
  • Autosomal dominant
Age of onset Adolescence / Young adulthood
ICD 10 code
  • E28.2
MIM number
Synonym(s) PCOS
Polycystic ovarian disease
Polycystic ovary syndrome

Summary

Stein-Leventhal syndrome is an endocrine disorder characterised by hyperandrogenism, hirsutism, ovulatory dysfunction leading to infertility and menstrual irregularities, polycystic ovaries and obesity. Patients with this syndrome are at increased risk of developing diabetes and heart disease. Prevalence estimates vary between studies but the syndrome is generally thought to affect between 4 and 12% of women of reproductive age, thus this is not a rare disease. The aetiology remains unknown. *Author: Orphanet (October 2006)*.

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