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Giant cell arteritis

Orpha number ORPHA397
Prevalence of rare diseases 1-9 / 100 000
Inheritance
  • Sporadic
Age of onset Adulthood
ICD 10 code
  • M31.6
MIM number
Synonym(s) Horton disease
Temporal arteritis

Summary

Giant cell arteritis (GCA) or temporal arteritis is a systemic vasculitis which involves large and medium-sized vessels, especially the extracranial branches of the carotid artery, usually in persons older than 50 years. Feared complications of GCA are permanent visual loss, ischaemic strokes and thoracic and abdominal aortic aneurysms. The treatment consists of high-dose steroids. Mortality in patients with GCA seems to be similar to that of controls, probably due to a correct diagnosis and management. GCA is the most common systemic vasculitis in Western countries. The incidence rates described in European countries are around 20:100 000 persons older than 50 years. *Author: Dr JM Calvo-Romero (June 2003)*.

Detailed information

Review article
Article for general public
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