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FRANCE

AQUITAINE
BORDEAUX

Accreditation
Predisposition molecular diagnosis of familial nonpolyposis colon cancer (MSH2, MSH6 and MLH1 genes)
CLCC Institut Bergonié
Purpose(s) : Post-natal diagnosis, Risk assessment
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Mutation scanning/screening and sequence analysis of selected exons, Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, MLPA based techniques, Array based techniques

FRANCE

RHONE-ALPES
LYON

Accreditation
Diagnosis of nonpolyposis colon cancer (Panel HNPCC MASTR Plus)
CLCC Léon Bérard
Purpose(s) : Post-natal diagnosis, Pre-symptomatic diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Mutation scanning/screening and sequence analysis of selected exons, Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, PCR based techniques, MLPA based techniques

FRANCE

NORD-PAS-DE-CALAIS
LILLE

Accreditation
Molecular diagnosis of hereditary nonpolyposis colon cancer (EPCAM, MLH1, MSH2, MSH6 and PMS2 genes ; MLH1 gene methylation ; microsatellites instability)
CHRU de Lille - Centre de Biologie Pathologie Génétique
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Methylation analysis

FRANCE

PROVENCE-ALPES-COTE D'AZUR
MARSEILLE

Accreditation
Molecular diagnosis of familial non polyposis colon cancer : search for mutations and big stature rearragements in MLH1, MSH2, MSH6, PMS2 genes
CLCC Institut Paoli Calmettes
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Mutation scanning/screening and sequence analysis of selected exons, Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

GERMANY

Nordrhein-Westfalen
DÜSSELDORF

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes)
Heinrich-Heine-Universität Düsseldorf
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

GERMANY

Hamburg
HAMBURG

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes)
Labor Lademannbogen
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

FRANCE

ILE-DE-FRANCE
BOBIGNY

Accreditation
Colon cancer, familial, non polyposis : microsatellites anomalies research (MLH1 and MSH2 genes)
CHU Paris Seine-Saint-Denis - Hôpital Avicenne
Purpose(s) : Post-natal diagnosis, Risk assessment
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons, Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

FRANCE

PAYS DE LA LOIRE
NANTES

Accreditation
Molecular diagnosis of colon cancer, familial nonpolyposis predisposition (MLH1, MSH6, PMS2 and MSH2 genes)
CHU de Nantes - Institut de Biologie
Purpose(s) : Post-natal diagnosis, Pre-symptomatic diagnosis, Risk assessment
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Mutation scanning/screening and sequence analysis of selected exons, Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing

FINLAND

Finland
OULU

Accreditation
Molecular diagnosis of nonpolyposis colon cancer (MLH1 gene)
Oulu University Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

GERMANY

Nordrhein-Westfalen
BOCHUM

Accreditation
Molecular diagnosis of HNPCC syndrome (MLH1, MSH2, MSH6, PMS2 genes)
Ruhr-Universität Bochum
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

BELGIUM

VLAAMS BRABANT
LEUVEN

Accreditation
Molecular diagnosis of Nonpolyposis colon cancer (MLH1, MSH2, MSH6, TACSTD1 genes)
University Hospitals Leuven - Gasthuisberg
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

FRANCE

ILE-DE-FRANCE
PARIS

Accreditation
Molecular diagnosis of colon cancer, familial nonpolyposis predisposition (MSH6, MLH1, MSH2 genes)
CHU Paris IdF Ouest - HEGP Hôpital Européen Georges Pompidou
Purpose(s) : Post-natal diagnosis, Pre-symptomatic diagnosis, Risk assessment
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

BELGIUM

OOST-VLAANDEREN
GENT

Accreditation
Molecular diagnosis of HNPCC- nonpolyposis colon cancer (MSH2, MLH1, MSH6 genes: mutation analysis)
Center for Medical Genetics Gent
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

BELGIUM

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS

Accreditation
Molecular diagnosis of Familial nonpolyposis colon cancer (MLH1 &MSH2 gene)
Erasme Hospital - ULB
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

SWITZERLAND

Suisse Romande
GENÈVE

Accreditation
Molecular diagnosis of hereditary non polyposis colon cancer (MLH1, MSH2, MSH6 and PMS2 genes : microsatellite instability)
Hôpitaux Universitaires de Genève HUG
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

UNITED KINGDOM

Greater Manchester
MANCHESTER

Accreditation
Molecular diagnosis of Familial Non Polyposis Colon Cancer - HNPCC (MLH1, MSH2 and MSH6 genes: mutation scanning by bi-directional DNA sequence analysis)
St Mary's Hospital
Purpose(s) : Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons

UNITED KINGDOM

West Midlands
BIRMINGHAM

GERMANY

Sachsen
DRESDEN

Accreditation
Molecular diagnosis of HNPCC syndrome (MLH1, MSH2, MSH6 genes/ microsatellite instability)
Mitteldeutscher Praxisverbund Humangenetik
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

UNITED KINGDOM

South Glamorgan
CARDIFF

Accreditation
Molecular diagnosis of Familial Non Polyposis Colon Cancer (HNPCC, MSI analysis and MLH, MSH2 and MSH6 genes: Sequencing and dosage analysis)
University Hospital of Wales
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

UNITED KINGDOM

Wiltshire
SALISBURY

Accreditation
Molecular diagnosis of Hereditary Nonpolyposis Colorectal Cancer - HNPCC (hMLH1, hMSH2 and hMSH6: by DHPLC and sequencing)
Salisbury District Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

UNITED KINGDOM

Greater London
HARROW

Accreditation
Molecular diagnosis of Familial Non Polyposis Colon Cancer - HNPCC (MLH1, MSH2 & MSH6 genes)
North West London Hospitals NHS - Northwick Park & St Marks Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

GERMANY

Baden-Württemberg
MANNHEIM

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes)
Zentrum für Humangenetik Mannheim
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

GERMANY

Bayern
MÜNCHEN

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2 and MSH6 genes)
Zweigniederlassung der synlab MVZ Augsburg GmbH
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

GERMANY

Bayern
REGENSBURG

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes)
Universitätsklinikum Regensburg
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

NETHERLANDS

Noord-Holland
AMSTERDAM

Accreditation
Molecular diagnosis of Hereditary Non-Polyposis Colorectal Cancer (MLH1, MSH2, MSH6 and PMS2 gene and search for microsatellite instability)
VUmc - VU medisch centrum
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

NETHERLANDS

Zuid-Holland
LEIDEN

Accreditation
Molecular diagnosis of Hereditary Non-Polyposis Colorectal Cancer (MLH1, MSH2, MSH6 and PMS2 gene)
LUMC - Leids Universitair Medisch Centrum
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

NETHERLANDS

Gelderland
NIJMEGEN

Accreditation
Molecular diagnosis of Lynch Syndrome (MLH1, MSH2, MSH6 and PMS2 gene)
Radboudumc - Radboud universitair medisch centrum
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

SPAIN

Cataluña
BARCELONA

Accreditation
Molecular Diagnosis of Colon cancer, familial nonpolyposis. APC gene
Laboratorio de Análisis Dr. Echevarne
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

SPAIN

Murcia
EL PALMAR

Accreditation
Diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6 and PMS2 genes)
Centro de Bioquímica y Genética Clínica
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, MLPA based techniques

BELGIUM

HAINAUT
GOSSELIES

Accreditation
Molecular diagnosis of Familial nonpolyposis colon cancer (MLH1 gene)
Institut de Pathologie et de Génétique - Gosselies
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

NETHERLANDS

Noord-Holland
AMSTERDAM

Accreditation
Molecular diagnosis of Hereditary Non-Polyposis Colorectal Cancer (MLH1, MSH2, MSH6 and PMS2 gene)
AMC - Academisch Medisch Centrum
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

SPAIN

Comunidad Valenciana
ELCHE

Accreditation
Diagnosis of the colon cancer familial nonpolyposis (MLH1, MSH2, MSH6, PMS2, EPCAM genes)
Hospital General Universitario de Elche
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Methylation analysis, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

NETHERLANDS

Utrecht
UTRECHT

Accreditation
Molecular diagnosis of Hereditary Non-Polyposis Colon Cancer (MSH2 and MSH6 gene)
UMC Utrecht - Universitair Medisch Centrum Utrecht
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

GERMANY

Baden-Württemberg
FREIBURG

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PIK3CA, PMS2 genes)
Praxis für Humangenetik Freiburg
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

UNITED KINGDOM

Tyne & Wear
NEWCASTLE UPON TYNE

Accreditation
Molecular diagnosis of Lynch Syndrome (HNPCC) and Familial Colorectal Cancer (MLH1 or MSH2 genes: Testing for known mutations in family members)
Newcastle upon Tyne Hospitals NHS Trust
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis

UNITED KINGDOM

Oxfordshire
OXFORD

Accreditation
Molecular diagnosis of Familial Non Polyposis Colon Cancer - HNPCC (MLH1, MSH2 and MSH6 genes: mutation screening by sequencing and dosage analysis by MLPA)
The Churchill Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons
Technical procedure(s) : MLPA based techniques

UNITED KINGDOM

Cambridgeshire
CAMBRIDGE

Accreditation
Molecular diagnosis of Familial Non Polyposis Colon Cancer - HNPCC (MLH1, MSH2 and MSH6: DNA sequencing and dosage)
Addenbrooke's Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

BELGIUM

HAINAUT
GOSSELIES

Accreditation
Molecular diagnosis of nonpolyposis colon cancer (MSH6 gene)
Institut de Pathologie et de Génétique - Gosselies
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

GERMANY

Nordrhein-Westfalen
DORTMUND

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PIK3CA, PMS2 genes; microsatellite instability testing)
Medizinisches Versorgungszentrum (MVZ) Dr. Eberhard und Partner
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

NETHERLANDS

Zuid-Holland
ROTTERDAM

Accreditation
Molecular diagnosis of Hereditary Non-Polyposis Colorectal Cancer (MLH1, MSH2 and MSH6 gene)
Erasmus MC, Faculteitsgebouw
Purpose(s) : Post-natal diagnosis, Pre-symptomatic diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

NETHERLANDS

Groningen
GRONINGEN

Accreditation
Molecular diagnosis of Hereditary Non-Polyposis Colorectal Cancer (EPCAM, MLH1, MSH2, MSH6 and PMS2 gene, Microsatellite Instability and MLH1 promotormethylation)
UMCG - Universitair Medisch Centrum Groningen
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Methylation analysis

UNITED KINGDOM

South Yorkshire
SHEFFIELD

Accreditation
Molecular diagnosis of Familial Non Polyposis Colon Cancer - HNPCC (MSH2, MLH1, MSH6: DNA sequencing; MSH2 and MLH1: MLPA dosage)
Sheffield Children's NHS Foundation Trust
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Technical procedure(s) : MLPA based techniques

BELGIUM

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUXELLES

Accreditation
Molecular diagnosis of Familial Non Polyposis Colon Cancer HNPCC (MLH1, MSH2, MSH6 & PMS2 genes)
Université Catholique de Louvain - UCL
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

GERMANY

Mecklenburg-Vorpommern
ROSTOCK

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (EPCAM, MLH1, MSH2, MSH6, PMS1, PMS2 genes)
Centogene AG
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

GERMANY

Baden-Württemberg
ULM

Accreditation
Molecular diagnosis of HNPCC syndrome (MLH1, MLH3, MSH2, MSH6, PMS1, PMS2 genes: sequencing, MLPA)
Universitätsklinikum Ulm
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

GERMANY

Sachsen
LEIPZIG

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2 genes)
MVZ Labor Dr. Reising-Ackermann und Kollegen
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

GERMANY

Mecklenburg-Vorpommern
ROSTOCK

Accreditation
Molecular diagnosis of HNPCC syndrome (MLH1, MSH2, MSH6, PMS2 genes : sequencing/ MLPA/ microsatellite analysis)
Diagenom GmbH
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

FRANCE

AUVERGNE
CLERMONT-FERRAND

Accreditation
Molecular diagnosis of hereditary non polyposis colon cancer (MLH1, MSH2 and MSH6 genes)
CLCC Jean Perrin
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Mutation scanning/screening and sequence analysis of selected exons, Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

GERMANY

Bayern
MÜNCHEN

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes)
Medizinisch Genetisches Zentrum München
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, Whole Exome Sequencing (WES)

GERMANY

Niedersachsen
HANNOVER

Accreditation
Molecular diagnosis of HNPCC syndrome (MLH1, MSH2, MSH6, PMS2 genes)
Medizinische Hochschule Hannover
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

BELGIUM

OOST-VLAANDEREN
GENT

Accreditation
Molecular screening for HNPCC - nonpolyposis colon cancer (MSI analysis)
Center for Medical Genetics Gent
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

GERMANY

Bayern
NEU-ULM

Accreditation
Molecular diagnosis of HNPCC syndrome (MLH1, MLH3, MSH2, MSH6, PMS1, PMS2 genes)
Paxis und Labor Dr. med Karl Mehnert
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

NETHERLANDS

Limburg
MAASTRICHT

Accreditation
Molecular diagnosis of Hereditary Nonpolyposis Colorectal Cancer (MLH1, MSH2 and MSH6 gene)
AZM - Academisch Ziekenhuis Maastricht
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ESTONIA

Tartu
TARTU

Accreditation
Molecular diagnosis of hereditary nonpolyposis colon cancer (Sequencing: MLH1, MSH2, MSH6; MLPA: MLH1, MSH2; microsatellite instability)
Asper Biotech Ltd.
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, MLPA based techniques

GERMANY

Rheinland-Pfalz
MAINZ

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes)
Universitätsmedizin Mainz
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

UNITED KINGDOM

Avon
BRISTOL

Accreditation
Molecular diagnosis of Hereditary nonpolyposis colon cancer (by MSI, BRAF and acquired KRAS mutation testing)
Southmead Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Methylation analysis
Technical procedure(s) : BS-Pyrosequencing

GERMANY

Nordrhein-Westfalen
KÖLN

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes)
Praxisgemeinschaft für Laboratoriumsmedizin und Humangenetik
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

GERMANY

Rheinland-Pfalz
INGELHEIM AM RHEIN

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes)
Bioscientia Institut für Medizinische Diagnostik GmbH
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

AUSTRIA

STEIERMARK
GRAZ

Accreditation
Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS1, PMS2, EPCAM, and TGFBR2 genes)
Medizinische Universität Graz
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

AUSTRIA

STEIERMARK
GRAZ

Accreditation
Molecular diagnosis of Lynch syndrome (MLH1, MSH2, MSH6, PMS1, PMS2, EPCAM, and TGFBR2 gene)
Medizinische Universität Graz
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

GERMANY

Hessen
BAD NAUHEIM

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1 and MSH2 genes)
Centrum für Humangenetik
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

GERMANY

Hamburg
HAMBURG

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (microsatellites, MLH1, MSH2, MSH6, PMS1, PMS2 genes)
MVZ Fenner & Krasemann
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

GERMANY

Niedersachsen
HANNOVER

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2 and MSH6 genes)
amedes genetics im MVZ wagnerstibbe
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing

GERMANY

Baden-Württemberg
KARLSRUHE

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS1, PMS2 genes)
Labor PD Dr. Volkmann und Kollegen
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

UNITED KINGDOM

Greater London
LONDON

Accreditation
Preimplantation molecular diagnosis of Hereditary Non Polyposis Colon Cancer - HNPCC, Lynch syndrome (MLH1 and MSH2: by linkage and mutation analysis)
Institute for Women's Health
Purpose(s) : Pre-implantation diagnosis
Specialty(ies) : Molecular genetics

CANADA

Ontario
MISSISSAUGA

Accreditation
Molecular Diagnosis of Lynch Syndrome
Trillium Health Partners- Credit Valley Site
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

AUSTRIA

TIROL
INNSBRUCK

Accreditation
Molecular diagnosis of Lynch syndrome (MLH1, MSH2, MSH6, and PMS2 genes)
Medizinische Universität Innsbruck
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

SWITZERLAND

Suisse Romande
LAUSANNE

Accreditation
Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes: entire coding region)
Unilabs Lausanne
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis
Technical procedure(s) : PCR based techniques

GERMANY

Bayern
WÜRZBURG

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes)
Universität Würzburg - Biozentrum
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, MLPA based techniques

SPAIN

Comunidad Valenciana
ELCHE

Accreditation
Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1, BRAF genes / Sequence analysis: select exons, Methylation analysis, MLPA)
Hospital General Universitario de Elche
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Methylation analysis
Technical procedure(s) : MLPA based techniques

SWITZERLAND

Suisse Alémanique
SCHLIEREN

Accreditation
Molecular diagnosis of Lynch syndrome (hereditary colon cancer) (MLH1, MSH2, MSH6, PMS2, EPCAM genes)
Universität Zürich
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

CANADA

Ontario
OTTAWA

Accreditation
Molecular Diagnosis of Hereditary Colon Cancer (MLH1, MSH2 sequencing and MLPA)
Children's Hospital of Eastern Ontario
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

GERMANY

Bayern
MARTINSRIED

Accreditation
Molecular diagnosis of HNPCC syndrome (MLH1, MSH2, MSH6, PMS2 genes)
Zentrum für Humangenetik und Laboratoriumsdiagnostik (MVZ)
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

GERMANY

Bayern
MÜNCHEN

Accreditation
Molecular diagnosis of HNPCC syndrome (EPCAM, MLH1, MLH3, MSH2, MSH6, PMS2 genes)
Pränatalmedizin München
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

CANADA

Ontario
TORONTO

Accreditation
Molecular Diagnosis of Lynch Syndrome (MLH1, MSH2, MSH6 sequencing and MLPA, EPCAM MLPA, IHC and MSI)
Mount Sinai Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Technical procedure(s) : MLPA based techniques

GERMANY

Schleswig-Holstein
KIEL

Accreditation
Molecular diagnosis of HNPCC syndrome (MLH1, MSH2, MSH6, PMS2 genes)
Universitätsklinikum Schleswig-Holstein - Campus Kiel
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

GERMANY

Niedersachsen
GÖTTINGEN

Accreditation
Molecular diagnosis of HNPCC syndrome (EPCAM, MLH1, MSH2, MSH6, PMS2 genes)
Institut für Humangenetik der Universität Göttingen
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, MLPA based techniques

GERMANY

Nordrhein-Westfalen
KÖLN

Accreditation
Molecular diagnosis of HNPCC syndrome (MLH1, MSH2, MSH6, PMS2 genes)
laboratoriumsmedizin köln - Dres. med. Wisplinghoff und Kollegen
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

SWITZERLAND

Suisse Romande
LAUSANNE

Accreditation
Molecular diagnosis of HNPCC (EPCAM, MLH1, MSH2, MSH6, PMS2 genes)
Synlab Lausanne
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

GERMANY

Baden-Württemberg
HEIDELBERG

Accreditation
Molecular diagnosis of HNPCC syndrome (MLH1, MSH2, MSH6, PMS2 genes)
Institut für Humangenetik am Universitätsklinikum Heidelberg
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

FRANCE

AUVERGNE
CLERMONT-FERRAND

Accreditation
Diagnosis of cancer predisposing syndrome (Panel)
CLCC Jean Perrin
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons
Technical procedure(s) : NGS sequencing (except WES)

FRANCE

ILE-DE-FRANCE
PARIS

Accreditation
Diagnosis of Lynch syndrome (Panel)
CLCC Institut Curie
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, MLPA based techniques

FRANCE

ILE-DE-FRANCE
PARIS

Accreditation
Diagnosis of pancreatic tumors (Panel)
CLCC Institut Curie
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, MLPA based techniques

FRANCE

ILE-DE-FRANCE
PARIS

Accreditation
Diagnosis of ovarian tumors (Panel)
CLCC Institut Curie
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, MLPA based techniques

FRANCE

ILE-DE-FRANCE
PARIS

Accreditation
Diagnosis of digestive tract tumor (Panel)
CLCC Institut Curie
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, MLPA based techniques

FRANCE

NORD-PAS-DE-CALAIS
LILLE

Accreditation
Diagnosis of intestinal polyposis syndrome (Panel)
CHRU de Lille - Centre de Biologie Pathologie Génétique
Purpose(s) : Post-natal diagnosis, Pre-symptomatic diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Sequence analysis: entire coding region, Methylation analysis, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, MLPA based techniques, BS-Pyrosequencing

FRANCE

BRETAGNE
RENNES

Accreditation
Diagnosis of predisposition to intestinal polyposis and digestive tract cancers (Panel)
CHU de Rennes - Hôpital Pontchaillou
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons
Technical procedure(s) : NGS sequencing (except WES)

CANADA

Ontario
MISSISSAUGA

Accreditation
Molecular Analysis of MLH1 Promoter Methylation/BRAF in Colon Cancer Tissue
Trillium Health Partners- Credit Valley Site
Purpose(s) : Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Methylation analysis
Technical procedure(s) : PCR based techniques, BS-Pyrosequencing

SPAIN

Cataluña
L'HOSPITALET DE LLOBREGAT

Accreditation
Diagnosis of hereditary breast, colon and ovarian cancer syndromes (gene panel)
Reference Laboratory Genetics
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES)

FRANCE

BASSE-NORMANDIE
CAEN

Accreditation
Search for RER phenotype in colon cancer
CLCC François Baclesse
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Uniparental disomy study

GERMANY

Bayern
WÜRZBURG

Accreditation
Molecular diagnosis of cancers predisposition by TruSight Cancer panel (NGS panel)
Universität Würzburg - Biozentrum
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES)

GERMANY

Baden-Württemberg
ULM

Accreditation
Molecular diagnosis of cancers predisposition by TruSight Cancer panel (NGS panel)
Universitätsklinikum Ulm
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES)

IRELAND

County Dublin
DUBLIN

Accreditation
Molecular Diagnosis of Lynch Syndrome (MLH1, MSH2, MSH6 or PMS2)
National Centre for Medical Genetics
Purpose(s) : Antenatal diagnosis, Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis
Technical procedure(s) : MLPA based techniques

UNITED KINGDOM

Merseyside
LIVERPOOL

Accreditation
Molecular diagnosis of Familial Non Polyposis Colon Cancer - HNPCC (MLH1, MSH2, MSH6 genes)
Liverpool Women's NHS Foundation Trust
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

UNITED KINGDOM

West Yorkshire
LEEDS

Accreditation
Molecular diagnosis of Familial Non Polyposis Colon Cancer, HNPCC (sequence and MLPA dosage analysis of MLH1, MSH2, MSH6 & PMS2 genes)
St James's University Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Technical procedure(s) : MLPA based techniques

UNITED KINGDOM

Tayside
DUNDEE

Accreditation
Molecular diagnosis of Hereditary Non Polyposis Colon Cancer - HNPCC, Lynch syndrome (MLH1 gene sequence analysis and MSI analysis of tumour tissue)
Ninewells Hospital and Medical School
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

GERMANY

Bayern
BAD STEBEN

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes)
Institut für angewandte Humangenetik und Onkogenetik
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

UNITED KINGDOM

West Yorkshire
LEEDS

Accreditation
Molecular diagnosis of Turcot syndrome (PMS2 gene)
St James's University Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis
Technical procedure(s) : Sanger sequencing

BELGIUM

HAINAUT
GOSSELIES

Accreditation
Molecular TherapID KRAS mutation test
DNA VISION SA
Purpose(s) : Somatic genetics
Specialty(ies) : Molecular genetics

SWEDEN

Västra Götalandsregionen
GÖTEBORG

Accreditation
Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2 and MSH6 genes: microsatellite instability)
Sahlgrenska Universitessjukhuset
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

UNITED KINGDOM

Nottinghamshire
NOTTINGHAM

Accreditation
Molecular diagnosis of Familial Non Polyposis Colorectal Cancer -HNPCC (MLH1, MSH2 and MSH6 genes: sequencing and MLPA)
Nottingham City Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Technical procedure(s) : MLPA based techniques

UNITED KINGDOM

Antrim and Newtownabbey
BELFAST

Accreditation
Molecular diagnosis of Familial Non Polyposis Colorectal Cancer -HNPCC (MLH1, MSH2 and MSH6 genes: sequencing and MLPA)
Belfast City Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Technical procedure(s) : MLPA based techniques

GERMANY

Bayern
MARTINSRIED

Accreditation
Molecular diagnosis of HNPCC syndrome (microsatellite instability in tumor tissue)
Zentrum für Humangenetik und Laboratoriumsdiagnostik (MVZ)
Purpose(s) : Somatic genetics
Specialty(ies) : Molecular genetics

SLOVAKIA

Bratislavsky kraj
BRATISLAVA

Accreditation
Molecular diagnosis of hereditary nonpolyposis colorectal cancer (MLH1, MSH2 and MSH6 genes: all exons including intron bounderies ; microsatellite instability)
Onkologicky ustav sv. Alzbety s.r.o.
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

CANADA

Terre-Neuve-et-Labrador
ST. JOHN'S

Accreditation
Molecular Diagnosis of Hereditary Nonpolyposis Colon Cancer (MSH2 c.942+3A>T mutation)
Health Sciences Centre
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

CANADA

Ontario
LONDON

Accreditation
Molecular Diagnosis of Hereditary Cancer Predisposition - Comprehensive NGS Panel (25 genes)
London Health Sciences Centre
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES)

CANADA

Ontario
LONDON

Accreditation
Molecular Diagnosis of High Penetrance Hereditary Cancer Predisposition - Comprehensive NGS Panel (16 genes)
London Health Sciences Centre
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES)

CANADA

Ontario
LONDON

Accreditation
Molecular Diagnosis of Colorectal/Gastric Hereditary Cancer Predisposition - Comprehensive NGS Panel (15 genes)
London Health Sciences Centre
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES)

CANADA

Ontario
TORONTO

Accreditation
Molecular Diagnosis of Lynch Syndrome- Comprehensive NGS Panel (4 genes) and del/dup (4 genes plus EPCAM)
Toronto General Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), MLPA based techniques

CANADA

Ontario
TORONTO

Accreditation
Molecular Diagnosis of Lynch Syndrome (MLH1 methylation in blood)
Toronto General Hospital
Purpose(s) : Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Methylation analysis
Technical procedure(s) : MLPA based techniques

FRANCE

MIDI-PYRENEES
TOULOUSE

Accreditation
Diagnosis of endocrine tumors (Panel)
CHU de Toulouse - Hôpital Purpan
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons
Technical procedure(s) : NGS sequencing (except WES)

FRANCE

ILE-DE-FRANCE
PARIS

Molecular diagnosis of nonpolyposis colon cancer (Panel)
CHU Paris-GH La Pitié Salpêtrière-Charles Foix - Hôpital Pitié-Salpêtrière
Purpose(s) : Post-natal diagnosis, Pre-symptomatic diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, MLPA based techniques

FRANCE

LANGUEDOC-ROUSSILLON
MONTPELLIER

Diagnosis of nonpolyposis colon cancer (Panel and RER phenotype)
CHRU de Montpellier - Hôpital Arnaud de Villeneuve
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons
Technical procedure(s) : NGS sequencing (except WES)

FRANCE

ALSACE
STRASBOURG

Search for RER phenotype in colon cancer
CHU de Strasbourg - Hôpital de Hautepierre
Purpose(s) : Somatic genetics
Specialty(ies) : Molecular genetics

ITALY

CAMPANIA
NAPOLI

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MLH3, MSH2, MSH6 genes, microsatellite analysis)
Biotecnologie Avanzate Srl
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ITALY

FRIULI VENEZIA GIULIA
AVIANO

Molecular diagnosis of hereditary nonpolyposis colon cancer (MSH2, MLH1, MSH6 genes)
Centro di Riferimento Oncologico
Purpose(s) : Post-natal diagnosis, Pre-symptomatic diagnosis, Risk assessment
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Sequence analysis: entire coding region, Methylation analysis, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, PCR based techniques, MLPA based techniques

FRANCE

LORRAINE
VANDOEUVRE-LÈS-NANCY

Molecular diagnosis of predisposition to colon cancer (MLH1, MSH2 and MSH6 genes)
CHU de Nancy - Hôpital de Brabois
Purpose(s) : Post-natal diagnosis, Risk assessment
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Mutation scanning/screening and sequence analysis of selected exons, Sequence analysis: entire coding region, Methylation analysis, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

SPAIN

Andalucía
SEVILLA

Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1, MSH2, MSH6 and PMS2 genes / deletions and duplications)
Hospital Universitario Virgen del Rocío
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Deletion / Duplication analysis

SPAIN

Cataluña
BARCELONA

Diagnosis of Lynch syndrome (MLH1, MSH2, MSH6 genes)
Centro de Diagnóstico Biomédico - CDB
Purpose(s) : Antenatal diagnosis, Post-natal diagnosis, Pre-symptomatic diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), MLPA based techniques

ITALY

LOMBARDIA
VARESE

'Immunohistochemistry and molecular diagnosis of familial nonpolyposis colon cancer (Lynch syndrome or HNPCC; MSH2, MSH6, PMS2, MLH1 genes)'
A.O.U. Ospedale di Circolo e Fondazione Macchi - Università dell'Insubria
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics, Biochemical genetics
Objective(s) : Protein expression
Technical procedure(s) : Immunohistochemistry

ITALY

PIEMONTE
TORINO

Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1, MSH2 genes)
A.O. Città della Salute e della Scienza di Torino - Ospedale Molinette
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

SWITZERLAND

Suisse Alémanique
BASEL

Molecular diagnosis of Hereditary Non Polyposis Colorectal Cancer (HNPCC)
Universitätsspital Basel
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

FRANCE

ILE-DE-FRANCE
VILLEJUIF

Molecular diagnosis of familial nonpolyposis colon cancer (search for microsatellite instabilities and MLH1, MSH2 and MSH6 genes)
CLCC Institut Gustave Roussy
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Uniparental disomy study, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

GERMANY

Nordrhein-Westfalen
BONN

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6 genes)
Universitätsklinikum Bonn
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

SPAIN

Galicia
SANTIAGO DE COMPOSTELA

Molecular diagnosis of colon cancer familial nonpolyposis (MLH1, MSH2, MSH6, PMS2 genes)
CHUS - Complejo Hospitalario Universitario de Santiago
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

GERMANY

Niedersachsen
OSNABRÜCK

Molecular diagnosis of HNPCC syndrome (EPCAM, MLH1, MLH3, MSH2, MSH6, PMS1, PMS2, TGFBR2 genes)
Praxis Dres. Gencik
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

FRANCE

MIDI-PYRENEES
TOULOUSE

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6 and EPCAM genes)
IUCT Oncopole - CLCC Institut Claudius Regaud
Purpose(s) : Post-natal diagnosis, Pre-symptomatic diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

FRANCE

ILE-DE-FRANCE
VILLEJUIF

Screening of nonpolyposis colon cancer : protein immunohistochemical analyses
CLCC Institut Gustave Roussy
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Biochemical genetics
Objective(s) : Protein expression
Technical procedure(s) : Immunohistochemistry

PORTUGAL

SUL
LISBOA

Molecular diagnosis of hereditary nonpolyposis colorectal cancer (MLH1, MSH2 and MSH6 genes)
Instituto Nacional de Saúde Dr. Ricardo Jorge - Lisboa
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

PORTUGAL

NORTE
PORTO

Molecular diagnosis of nonpolyposis colon cancer (MSH2, MLH1, MSH6 and PMS2 genes, and microsatellite analysis)
Instituto Português de Oncologia do Porto, EPE / IPOFG - CRO Porto
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics

SPAIN

Andalucía
MÁLAGA

Molecular diagnosis of familial nonpolyposis colon cancer. KRAS gene
Hospital Regional Universitario de Málaga - Hospital General
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

NETHERLANDS

Noord-Holland
AMSTERDAM

Molecular diagnosis of Hereditary non-polyposis colorectal cancer (MLH1, MSH2 and MSH6 gene; search for microsatellite instability and methylation of MLH1 promoter)
Het Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Methylation analysis

TURKEY

TURKEY
ISTANBUL

Predisposition molecular diagnosis of familial nonpolyposis colon cancer
Acibadem healthcare group
Purpose(s) : Post-natal diagnosis, Risk assessment
Specialty(ies) : Molecular genetics

SPAIN

Comunidad Valenciana
PATERNA

Diagnosis of the familial nonpolyposis colon cancer (MLH1, MSH2 MSH6, PMS1 y PMS2 genes)
Sistemas Genómicos S.L.
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing

ITALY

TOSCANA
PISA

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6 genes)
Azienda Ospedaliero Universitaria Pisana - Ospedale S. Chiara
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing

ITALY

LAZIO
ROMA

Molecular diagnosis of proneness to familial nonpolyposis colon cancer (MSH2 and MLH1 genes)
Laboratorio Genoma
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

GERMANY

Nordrhein-Westfalen
MÜNSTER

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes)
Institut für Humangenetik des Universitätsklinikums Münster
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

ITALY

LOMBARDIA
MONZA

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6 genes)
Consorzio per la Genetica Molecolare Umana
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

DENMARK

Syddanmark
VEJLE

Molecular diagnosis of hereditary nonpolyposis colorectal cancer (microsatellite instability; MLH1 promoter methylation detected by methylation-senstivie MLPA)
Sygehus Lillebaelt Vejle Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Methylation analysis
Technical procedure(s) : MLPA based techniques

GERMANY

Sachsen
DRESDEN

Immunohistochemical and molecular diagnosis of HNPCC syndrome (MLH1, PMS2, MSH2, MSH6 genes and microsatellite analysis)
Universitätsklinikum Carl Gustav Carus an der TU Dresden
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics, Biochemical genetics
Objective(s) : Sequence analysis: entire coding region, Protein expression
Technical procedure(s) : Sanger sequencing, Immunohistochemistry

SPAIN

Madrid
MADRID

Molecular diagnosis of the familial nonpolyposis colon cancer (MSH2, MSH6, MLH1, PMS2 genes)
INGEMM - Instituto de Genética Médica y Molecular (IdiPAZ)
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

GERMANY

Hamburg
HAMBURG

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes)
Pränatalzentrum Hamburg und Humangenetik
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

GERMANY

Baden-Württemberg
STUTTGART

Molecular diagnosis of familial nonpolyposis colon cancer (EPCAM, MLH1, MSH2, MSH6, PMS2 genes: sequencing / MLPA)
Praxis für Humangenetik und Prävention
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

SPAIN

País Vasco
SAN SEBASTIÁN

Molecular diagnosis of colon cancer, familial nonpolyposis (microsatellite inestability; large deletions by MLPA kit P003, MLPA kit ME011; entire coding sequence of MLH1, MSH2 and MSH6 genes; BRAF gene / mutation V600E)
Hospital Universitario Donostia
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : MLPA based techniques

SPAIN

Andalucía
MÁLAGA

Diagnosis of Lynch syndrome (MSH2, MLH1, PMS2 genes)
Genetaq
Purpose(s) : Antenatal diagnosis, Post-natal diagnosis, Pre-symptomatic diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, MLPA based techniques

PORTUGAL

NORTE
PORTO

Molecular diagnosis MLH1 and MSH2-related hereditary nonpolyposis colorectal cancer: microsatelite instability analysis
CGC Genetics / Centro de Genética Clínica
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics

FRANCE

BRETAGNE
BREST

Molecular diagnosis of hereditary nonpolyposis colorectal cancer (RER phenotype; p.V600E mutation in the BRAF gene)
CHRU de Brest - Hôpital Morvan
Purpose(s) : Somatic genetics
Specialty(ies) : Molecular genetics

PORTUGAL

SUL
LISBOA

Molecular diagnosis of hereditary nonpolyposis colorectal cancer (MLH1, MSH2, MSH6, BRAF and KRAS genes)
Faculdade de Medicina da Universidade de Lisboa
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

SPAIN

Andalucía
ARMILLA

Molecular diagnosis of hereditary nonpolyposis colon cancer (entire coding sequence of MLH1, MSH2 and MSH6 genes)
Lorgen G.P.
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region

SPAIN

Cataluña
BARCELONA

Preimplantation genetic diagnosis of hereditary nonpolyposis colon cancer (MSH2 gene)
Reprogenetics Spain S.A.
Purpose(s) : Pre-implantation diagnosis
Specialty(ies) : Molecular genetics

SPAIN

Comunidad Valenciana
PATERNA

Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1, MSH6, MSH2, PMS1, PMS2 genes / entire coding sequence)
IMEGEN - Instituto de Medicina Genómica
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, Whole Exome Sequencing (WES)

SPAIN

Cataluña
L'HOSPITALET DE LLOBREGAT

Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1, MSH2 and MSH6 genes - sequencing/MLPA)
ICO L'Hospitalet
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Technical procedure(s) : MLPA based techniques

GERMANY

Baden-Württemberg
STUTTGART

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes)
Klinikum Stuttgart - Standort Olgahospital
Purpose(s) : Post-natal diagnosis, Pre-symptomatic diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

GERMANY

Sachsen
DRESDEN

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes: sequencing / MLPA)
Gemeinschaftspraxis für Humangenetik
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

ITALY

LOMBARDIA
CREMONA

Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1, MSH2, MSH6, KRAS, PIK3CA genes; microsatellite instability analysis)
Azienda Ospedaliera Istituti Ospitalieri di Cremona
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

SPAIN

Cataluña
BARCELONA

Preimplantation genetic diagnosis of hereditary nonpolyposis colon cancer (MSH2 and MSH6 genes)
CME Barcelona
Purpose(s) : Pre-implantation diagnosis
Specialty(ies) : Molecular genetics

SPAIN

Castilla - León
VALLADOLID

Diagnosis of hereditary nonpolyposis colon cancer (MLH1, MSH2, MSH6 genes)
IBGM - Instituto de Biología y Genética Molecular
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, MLPA based techniques

SPAIN

Madrid
MADRID

Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1, MSH2, MSH6 genes)
Hospital Clínico San Carlos
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

SPAIN

La Rioja
LOGROÑO

Diagnosis of Lynch syndrome (MLH1, MSH2, MSH6 genes)
Fundación Rioja Salud - Centro de Investigación Biomédica de La Rioja
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

GERMANY

Sachsen
LEIPZIG

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2 and MSH6 genes)
Institut für Humangenetik am Universitätsklinikum Leipzig
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

SPAIN

País Vasco
SAN SEBASTIÁN

Diagnosis of Lynch syndrome (gene panel)
Onkologikoa
Purpose(s) : Post-natal diagnosis, Risk assessment
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing

SPAIN

Andalucía
SEVILLA

Diagnosis of Lynch syndrome (determination of microsatellite length changes)
Hospital Universitario Virgen del Rocío
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis
Technical procedure(s) : PCR based techniques

SPAIN

País Vasco
SAN SEBASTIÁN

Molecular diagnosis of hereditary colon cancer (MUTYH, EPCAM, MSH2, MSH6, MLH1, APC, BMPR1A, PTEN, MLH3, SMAD4, STK11 genes / array-CGH)
Policlínica Gipuzkoa
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Deletion / Duplication analysis
Technical procedure(s) : Array based techniques

SPAIN

Cataluña
TERRASSA

Diagnosis of Lynch syndrome (MLH1, MSH2, MSH6, PMS2, KRAS genes)
Consorci Sanitari de Terrassa
Purpose(s) : Post-natal diagnosis, Pharmacogenetics, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Sequence analysis: entire coding region, Methylation analysis
Technical procedure(s) : NGS sequencing (except WES), PCR based techniques, MLPA based techniques

PORTUGAL

NORTE
PORTO

Molecular diagnosis of EPCAM-related Lynch syndrome (EPCAM gene: sequencing of the entire coding region and deletion/duplication analysis)
CGC Genetics / Centro de Genética Clínica
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis

PORTUGAL

NORTE
PORTO

Molecular diagnosis of hereditary nonpolyposis colorectal cancer (MLH1, MSH2, MLH3, MSH6, BMPR1 and PMS2 genes: Sequencing of the entire coding region for MLH1, MSH2, MLH3, MSH6, BMPR1 genes and deletion/duplication analysis by MLPA for MLH1, MSH2, MSH6 and PMS2 genes)
CGC Genetics / Centro de Genética Clínica
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : MLPA based techniques

SPAIN

Comunidad Valenciana
SANT JOAN D'ALACANT

Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS1, PMS2 genes: entire coding sequence; MLH1, MSH2 genes: MLPA)
Centro Inmunológico de Alicante (CIALAB)
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : MLPA based techniques

SPAIN

Castilla - León
SALAMANCA

Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes / sequencing)
Universidad de Salamanca. Facultad de Medicina
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

PORTUGAL

NORTE
PORTO

Molecular diagnosis of Hereditary non-polyposis colorectal cancer (NGS panel for MLH1, MSH2, MSH6 PMS2 and EPCAM genes: Sequencing of the entire coding region)
CGC Genetics / Centro de Genética Clínica
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES)

PORTUGAL

NORTE
PORTO

Methylation analysis of the MLH1 gene promotor by ms-MLPA
CGC Genetics / Centro de Genética Clínica
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Methylation analysis
Technical procedure(s) : MLPA based techniques

SPAIN

Asturias
OVIEDO

Diagnosis of Lynch syndrome (MSH2, MSH6, PMS2, PMS2 genes)
IMOMA - Instituto de Medicina Oncológica y Molecular de Asturias
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Uniparental disomy study, Methylation analysis, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques, BS-Pyrosequencing

SPAIN

Cataluña
BARCELONA

Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1, MSH2, MSH6 genes)
Hospital del Mar
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

CANADA

Alberta
EDMONTON

Molecular Diagnosis of Hereditary Non-Polyposis Colorectal Cancer (MLPA, sequencing, targeted mutation analysis MLH1, MSH2, MSH6, PMS2)
University of Alberta
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis
Technical procedure(s) : MLPA based techniques

SPAIN

Comunidad Valenciana
PATERNA

Molecular diagnosis of hereditary nonpolyposis colon cancer (EPCAM gene / MLPA)
IMEGEN - Instituto de Medicina Genómica
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Technical procedure(s) : MLPA based techniques

GERMANY

Mecklenburg-Vorpommern
GREIFSWALD

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes: sequencing / MLPA)
Institut für Humangenetik der Universitätsmedizin Greifswald
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

SPAIN

Comunidad Valenciana
ELCHE

Diagnosis of Lynch syndrome (gene panel)
Bioarray
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), MLPA based techniques

GERMANY

Bayern
ERLANGEN

Molecular diagnosis of HNPCC syndrome (MLH1, MSH2, MSH6, PMS2 genes)
Humangenetisches Institut am Universitätsklinikum Erlangen
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

SPAIN

País Vasco
SAN SEBASTIÁN

Diagnosis of Lynch syndrome (MLH1, MSH2 and MSH6 genes)
DNA Data
Purpose(s) : Risk assessment
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), MLPA based techniques

FRANCE

ILE-DE-FRANCE
PARIS

Diagnosis of hereditary nonpolyposis colon cancer (Panel)
CHU Paris Centre - Hôpital Cochin
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons
Technical procedure(s) : NGS sequencing (except WES)

FRANCE

HAUTE-NORMANDIE
ROUEN

Diagnosis of digestive tract tumor (Panel)
Faculté de médecine et de pharmacie de Rouen
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons
Technical procedure(s) : NGS sequencing (except WES)

FRANCE

ILE-DE-FRANCE
PARIS

Diagnosis of predisposition to hemopathies (Panel)
CHU Paris - Hôpital Robert Debré
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons
Technical procedure(s) : NGS sequencing (except WES)

FRANCE

ILE-DE-FRANCE
PARIS

Predisposition to tumors (melanoma, pancreas, kidney, breast-ovary, colon, skin cancers) (Panel)
CHU Paris Nord-Val de Seine - Hôpital Xavier Bichat-Claude Bernard
Purpose(s) : Post-natal diagnosis, Pre-symptomatic diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing

FRANCE

ALSACE
STRASBOURG

Diagnosis of digestive tract tumor (Panel)
CHU de Strasbourg - Hôpital de Hautepierre
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, MLPA based techniques

SPAIN

País Vasco
SAN SEBASTIÁN

Diagnosis of colon cancer (panel)
DNA Data
Purpose(s) : Risk assessment
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES)

GERMANY

Sachsen
DRESDEN

Molecular diagnosis of cancers predisposition by TruSight Cancer panel (NGS panel)
Universitätsklinikum Carl Gustav Carus an der TU Dresden
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES)

GERMANY

Baden-Württemberg
FREIBURG

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS2 genes)
Institut für Humangenetik am Universitätsklinikum Freiburg
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Mutation scanning/screening and sequence analysis of selected exons, Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing

ITALY

PUGLIA
CASTELLANA GROTTE

Molecular diagnosis of familial nonpolyposis colon cancer (hMLH1, hMSH2, hMSH6 genes)
IRCCS "Saverio De Bellis"
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ITALY

PUGLIA
BARI

Molecular diagnosis of familial adenomatous polyposis (MLH1, MSH2, MSH6, MYH genes)
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ITALY

PUGLIA
BARI

Molecular diagnosis of Turcot syndrome (APC, MSH2, MLH1 genes)
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ITALY

PUGLIA
BARI

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6 genes)
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

FRANCE

CENTRE
TOURS

Molecular diagnosis of colon cancer, familial nonpolyposis (microsatellite instability)
CHRU de Tours - Hôpital Trousseau
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Uniparental disomy study

DENMARK

Jylland
ALBORG

Molecular diagnosis of familial nonpolyposis colon cancer
Alborg Sygehus Nord
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

DENMARK

Jylland
AARHUS

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6 and PMS2 gene sequencing and MLPA)
Aarhus Universitetshospital - Skejby
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Technical procedure(s) : MLPA based techniques

GREECE

ATTIKI
ATHENS

Molecular diagnosis of nonpolyposis colon cancer (MLH1 and MSH6 genes)
BIOGENOMICA
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ITALY

PIEMONTE
ORBASSANO

Molecular diagnosis of familial nonpolyposis colon cancer (MSH6 gene)
Azienda Ospedaliero-Universitaria San Luigi Gonzaga
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

SPAIN

Comunidad Valenciana
ALICANTE

Molecular diagnosis of nonpolyposis colon cancer
Análisis Genéticos ANCOR S.L.
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ITALY

TOSCANA
FIRENZE

Molecular diagnosis of colon cancer, familial nonpolyposis (MLH1, MSH2 and MSH6 genes)
Azienda Ospedaliero Universitaria Careggi - NEUROFARBA
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ITALY

LIGURIA
GENOVA

Molecular diagnosis of nonpolyposis colon cancer
Istituto Nazionale per la Ricerca sul Cancro - IST
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

CYPRUS

Cyprus
NICOSIA

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2, MSH6, PMS1 and PMS2 genes)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

GERMANY

Mecklenburg-Vorpommern
ROSTOCK

Molecular diagnosis of familial nonpolyposis colon cancer
Albrecht-Kossel-Institute for Neuroregeneration (AKos)
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

UNITED KINGDOM

Lothian
EDINBURGH

Molecular diagnosis of Familial Non Polyposis Colon Cancer - HNPCC (MSH2 and MSH6 genes)
Western General Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

CZECH REPUBLIC

Capital City Prague
PRAHA

Predisposition molecular diagnosis of familial nonpolyposis colon cancer (MSH2 and MLH1 genes)
Motol university hospital - 2nd Medical School Charles University Prague
Purpose(s) : Post-natal diagnosis, Risk assessment
Specialty(ies) : Molecular genetics

ROMANIA

BUCURESTI
BUCURESTI

Molecular diagnosis of predisposition to familial nonpolyposis colon cancer (MSI)
GeneticLab
Purpose(s) : Post-natal diagnosis, Risk assessment
Specialty(ies) : Molecular genetics

DENMARK

Fyn
ODENSE

Molecular diagnosis of susceptibility to familial nonpolyposis colon cancer (MLH1, MSH2 and MSH6 gene analysis by sequencing and MLPA)
Amplexa Genetics A/S
Purpose(s) : Post-natal diagnosis, Risk assessment
Specialty(ies) : Molecular genetics
Technical procedure(s) : MLPA based techniques

SWEDEN

Stockholms läns landsting
STOCKHOLM

Molecular diagnosis of familial non polyposis colon cancer (APC gene)
Karolinska University Hospital - Clinical Genetics
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

SWEDEN

Stockholms läns landsting
STOCKHOLM

Molecular diagnosis of familial non polyposis colon cancer (MLH1, MSH2, MSH6 and PMS2 genes)
Karolinska University Hospital - Clinical Genetics
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ITALY

PUGLIA
SAN GIOVANNI ROTONDO

Molecular diagnosis of familial non polyposis colon cancer (PMS1, PMS2, MLH1, MSH2, MSH6 genes)
IRCCS Ospedale Casa Sollievo della Sofferenza - Polamb. Giovanni Paolo II
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ISRAEL

ISRAEL
JERUSALEM

Molecular diagnosis of Hereditary Non-Polyposis Colorectal Cancer (MSH2, Mutation analysis)
Hadassah Ein Kerem - Hebrew University Medical Center
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ISRAEL

ISRAEL
RAMAT GAN

Molecular diagnosis of Colon cancer (APC, MSH2, Mutation analysis, PGD)
Sheba Medical Center
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ISRAEL

ISRAEL
PETAH TIKVA

Molecular diagnosis of Colon Cancer (MSH2, Mutation analysis)
Rabin Medical Center - Beilinson Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ISRAEL

ISRAEL
JERUSALEM

Molecular diagnosis of Colon Cancer, HNPCC (MSH2, Mutation analysis)
Shaare Zedek Medical Center
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ESTONIA

Tallinn
TALLINN

NORWAY

Østlandet
OSLO

Molecular diagnosis of familial non polyposis colon cancer (MLH1, MSH2 and MSH6 genes)
Oslo Universitetssykehus HF, Rikshospitalet
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ITALY

CAMPANIA
AVELLINO

Molecular diagnosis of colon cancer (KRAS gene)
Azienda Ospedaliera San Giuseppe Moscati
Purpose(s) : Somatic genetics
Specialty(ies) : Molecular genetics

GREECE

ATTIKI
ATHENS

Molecular diagnosis of hereditary nonpolyposis colorectal cancer (MLH1, MSH2 and MSH6 genes: full sequencing and screening of large genomic rearrangements by MLPA)
National center for scientific research Demokritos
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Technical procedure(s) : MLPA based techniques

FRANCE

ILE-DE-FRANCE
PARIS

Diagnosis of Lynch syndrome (MSH2 gene; NR21, NR24, NR22, BAT 25, BAT26 markers)
CHU Paris-GH St-Louis Lariboisière F.Widal - Hôpital Saint-Louis
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis
Technical procedure(s) : PCR based techniques

SPAIN

Madrid
MADRID

Molecular diagnosis of colon cancer, familial nonpolyposis (MSH2, MSH6 and MLH1 genes)
Centro Nacional de Investigaciones Oncológicas (CNIO)
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ITALY

EMILIA ROMAGNA
MELDOLA

Molecular diagnosis of familial nonpolyposis colon cancer
IRST - Istituto Scientifico Romagnolo per lo studio e la cura dei Tumori
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Mutation scanning/screening and sequence analysis of selected exons, Uniparental disomy study, Deletion / Duplication analysis
Technical procedure(s) : NGS sequencing (except WES), Sanger sequencing, MLPA based techniques

CZECH REPUBLIC

South Moravia
BRNO

Molecular diagnosis of familial nonpolyposis colon cancer (MSH2 gene)
Masaryk Memorial Cancer Institute
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ISRAEL

ISRAEL
TEL AVIV

Molecular diagnosis of hereditary non-polyposis colorectal cancer (MLH1, MSH2, MSH6 and PMS2 genes)
Pronto Diagnostics Ltd.
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ROMANIA

BUCURESTI
BUCURESTI

Postnatal molecular diagnosis of familial nonpolyposis colon cancer (MLH1 and MSH2 genes:deletion/duplication analysis by MLPA)
National institute of legal medicine
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Deletion / Duplication analysis
Technical procedure(s) : MLPA based techniques

SPAIN

Madrid
SAN SEBASTIÁN DE LOS REYES

'Diagnosis of Lynch syndrome (MLH1, MSH2, MSH6, PMS1, PMS2 genes; microsatellite instability: BAT25, BAT26, D5S346, D17S250, D2S123, NR21, NR22, NR24)'
Laboratorio de Genética Clínica, S.L.
Purpose(s) : Antenatal diagnosis, Post-natal diagnosis, Pre-symptomatic diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis, Mutation scanning/screening and sequence analysis of selected exons, Sequence analysis: entire coding region, Deletion / Duplication analysis
Technical procedure(s) : Sanger sequencing, MLPA based techniques

SPAIN

Comunidad Valenciana
VALENCIA

Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1 and MSH2)
INCLIVA
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

SPAIN

La Rioja
LOGROÑO

Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1 and MSH2 genes)
Hospital San Pedro
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

SPAIN

Madrid
MAJADAHONDA

Molecular diagnosis of hereditary nonpolyposis colon cancer (sequencing of MLH1, MSH2, MSH6 and PMS2 genes)
Genyca Innova
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ITALY

SARDEGNA
CAGLIARI

Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1, MSH2, MSH6 genes)
Ospedale "R. Binaghi"
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

ITALY

LAZIO
ROMA

Molecular diagnosis of predisposition to hereditary non polyposis colon cancer (MLH1, MSH2 genes)
USI - Unione Sanitaria Internazionale
Purpose(s) : Post-natal diagnosis, Risk assessment
Specialty(ies) : Molecular genetics

CANADA

Québec
MONTRÉAL

Molecular diagnosis of hereditary nonpolyposis colon cancer (MLH1, MSH2, MSH6 genes / microsatellite instability - 5 markers)
Hôpital général juif - Jewish General Hospital
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics

GERMANY

Berlin
BERLIN

Molecular diagnosis of cancer (NGS Cancer Panel)
ATG GenMed GmbH
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : NGS sequencing (except WES)

SPAIN

Comunidad Valenciana
PATERNA

Preimplantation genetic diagnosis of hereditary nonpolyposis colon cancer (MLH1, MSH2 genes)
Igenomix Spain
Purpose(s) : Pre-implantation diagnosis
Specialty(ies) : Molecular genetics

ITALY

PUGLIA
LECCE

Molecular diagnosis of colon cancer (KRAS gene)
Presidio Ospedaliero "Vito Fazzi" - ASL LE
Purpose(s) : Somatic genetics
Specialty(ies) : Molecular genetics

ITALY

PUGLIA
LECCE

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1, MSH2 genes)
Presidio Ospedaliero "Vito Fazzi" - ASL LE
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics

GERMANY

Berlin
BERLIN

Molecular diagnosis of familial nonpolyposis colon cancer (MLH1 and MSH2 genes: sequencing)
ATG GenMed GmbH
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing

UNITED KINGDOM

Lothian
EDINBURGH

Molecular diagnosis of Lynch Syndrome (HNPCC) and Familial Colorectal Cancer by sequencing of the entire coding region of the gene(s) plus copy number analysis (Genes: MSH2, MSH6)
Western General Hospital
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region

CYPRUS

Cyprus
NICOSIA

Microsatelite instability for colorectal cancer syndromes
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics

CYPRUS

Cyprus
NICOSIA

Analysis for known mutations f colorectal cancer syndromes (hMLH1 3p22.2)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis

CYPRUS

Cyprus
NICOSIA

Mutation screening of colorectal cancer syndromes (hMLH1 3p22.2)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons

CYPRUS

Cyprus
NICOSIA

Analysis for known mutations of colorectal cancer syndromes (hMSH2 2p21)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis

CYPRUS

Cyprus
NICOSIA

Mutation screening of colorectal cancer syndromes (hMSH2 2p21)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons

CYPRUS

Cyprus
NICOSIA

Mutation screening of colorectal cancer syndromes (hPMS1 2q32.2)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons

CYPRUS

Cyprus
NICOSIA

Analysis of known mutations for colorectal cancer syndromes (hPMS1 2q32.2)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis

CYPRUS

Cyprus
NICOSIA

Analysis of known mutations for colorectal cancer syndromes (hPMS2 7p22.1)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis

CYPRUS

Cyprus
NICOSIA

Mutation screening for colorectal cancer syndromes (hPMS2 7p22.1)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons

CYPRUS

Cyprus
NICOSIA

Mutation screening for colorectal cancer syndromes (hMSH6 2p16.3)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons

CYPRUS

Cyprus
NICOSIA

Analysis of known mutations for colorectal cancer syndromes (hMSH6 2p16.3)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis

CYPRUS

Cyprus
NICOSIA

Analysis of known mutations for colorectal cancer syndromes (MYH 1p34.1)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Targeted mutation analysis

CYPRUS

Cyprus
NICOSIA

Mutation screening for colorectal cancer syndromes (MYH 1p34.1)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics
Objective(s) : Mutation scanning/screening and sequence analysis of selected exons

CYPRUS

Cyprus
NICOSIA

Immunohistochemistry for colorectal cancer syndromes (hMLH1 3p22.2)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics

CYPRUS

Cyprus
NICOSIA

Immunohistochemistry for colorectal cancer syndromes (hMSH2 2p21)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics

CYPRUS

Cyprus
NICOSIA

Immunohistochemistry for colorectal cancer syndromes (hMLH6)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics

CYPRUS

Cyprus
NICOSIA

Immunohistochemistry for colorectal cancer syndromes (hPMS2 7p22.1)
The Cyprus Institute of Neurology and Genetics
Purpose(s) : Post-natal diagnosis, Somatic genetics
Specialty(ies) : Molecular genetics

HUNGARY

Dél-Alföld
SZEGED

Muir-Torre syndrome
University of Szeged Deparment of Medical Genetics
Purpose(s) : Post-natal diagnosis
Specialty(ies) : Molecular genetics
Objective(s) : Sequence analysis: entire coding region
Technical procedure(s) : Sanger sequencing