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Caption : Designated centres of expertise = Accreditation
Member of an ERN = ERN

FRANCE

ILE-DE-FRANCE
LE KREMLIN-BICÊTRE

ITALY

LIGURIA
GENOVA

POLAND

Warszawa
WARSAW

Gastrology and hepatology Clinic
Instytut "Pomnik-Centrum Zdrowia Dziecka"

SPAIN

Madrid
MADRID

Rare genetic cardiac diseases clinic
Fundación Jiménez Díaz

SWEDEN

Stockholms läns landsting
STOCKHOLM

Expert team for cholestasis in infants
Karolinska University Hospital - Solna

GERMANY

Bayern
MÜNCHEN

Hepatology clinic
Klinikum rechts der Isar der Technischen Universität München

GERMANY

Bayern
MÜNCHEN

Hepatology clinic
LMU Klinikum der Universität München - Campus Großhadern

GERMANY

Bayern
REGENSBURG

Rare hepatic diseases clinic
Universitätsklinikum Regensburg

GERMANY

Nordrhein-Westfalen
WUPPERTAL

Chronic inflammatory liver diseases clinic
HELIOS Universitätsklinikum Wuppertal - Universität Witten/Herdecke

GERMANY

Rheinland-Pfalz
MAINZ

Gastroenterology and hepatology clinic
Universitätsmedizin Mainz

ITALY

FRIULI VENEZIA GIULIA
TRIESTE

Centre of Expertise for metabolic liver diseases and rare biliary tract diseases
Azienda Ospedaliero-Universitaria "Ospedali Riuniti di Trieste"

POLAND

Warszawa
WARSAW

Clinic for rare hepatobiliary diseases
Instytut "Pomnik-Centrum Zdrowia Dziecka"

AUSTRIA

STEIERMARK
GRAZ

Gastroenterology and hepatology clinic
Medizinische Universität Graz

AUSTRIA

TIROL
INNSBRUCK

Pediatric endocrinology clinic
Medizinische Universität Innsbruck

AUSTRIA

TIROL
INNSBRUCK

Pediatric gastroenterology and hepatology
Medizinische Universität Innsbruck

CANADA

Manitoba
WINNIPEG

Genetics and Metabolism
Health Sciences Centre

CANADA

Ontario
MISSISSAUGA

Clinical Genetics, Credit Valley Site, Trillium Health Partners
Genetics Clinic, Credit Valley Hospital

CANADA

Ontario
TORONTO

Clinical and Metabolic Genetics Division
The Hospital for Sick Children and University of Toronto

CANADA

Québec
MONTRÉAL

Genetique Medicale
Centre hospitalier universitaire Sainte-Justine

CANADA

Québec
MONTRÉAL

Medical genetics pediatric clinic
Glen / McGill Univeristy Health Centre - Centre Universitaire de santé McGill

CANADA

Québec
MONTRÉAL

Medical genetics adult clinic
Glen / McGill Univeristy Health Centre - Centre Universitaire de santé McGill

CANADA

Québec
SHERBROOKE

Medical genetics service
CHU Sherbrooke - Hôpital Fleurimont

FRANCE

ILE-DE-FRANCE
PARIS

GERMANY

Baden-Württemberg
ESSLINGEN

Hepatology clinic
Klinikum Esslingen

GERMANY

Baden-Württemberg
FREIBURG

Hepatology clinic
Universitätsklinikum Freiburg

GERMANY

Baden-Württemberg
TÜBINGEN

Hepatology clinic
Behandlungs- und Forschungszentrum für Seltene Erkrankungen ZSE Tübingen

GERMANY

Baden-Württemberg
TÜBINGEN

Hepatic and biliary tract diseases clinic
Department für Innere Medizin - Medizinische Universitätsklinik Tübingen

GERMANY

Bayern
BAMBERG

GERMANY

Bayern
BAMBERG

Hepatology clinic
Klinikum Bamberg

GERMANY

Bayern
ERLANGEN

Hepatology clinic
Internistisches Zentrum des Universitätsklinikums Erlangen

GERMANY

Bayern
ERLANGEN

Gastroenterology and hepatology clinic
Kinder- und Jugendklinik des Universitätsklinikums Erlangen

GERMANY

Bayern
MÜNCHEN

Visceral and thorax surgery clinic
Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital

GERMANY

Bayern
MÜNCHEN

Care-for-Rare Center (CRCHauner): specialised clinic for children with rare diseases
Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital

GERMANY

Bayern
MÜNCHEN

Hepatology clinic
Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital

GERMANY

Berlin
BERLIN

Hepatology clinic
Charité - Universitätsmedizin Berlin (CVK)

GERMANY

Hamburg
HAMBURG

Gastroenterology and hepatology clinic
UKE - Universitätsklinikum Hamburg-Eppendorf

GERMANY

Hessen
FRANKFURT AM MAIN

Gastroenterology and hepatology clinic
Klinikum der Johann Wolfgang Goethe-Universität Frankfurt

GERMANY

Hessen
FRANKFURT AM MAIN

Interdisciplinary liver center
Klinikum der Johann Wolfgang Goethe-Universität Frankfurt

GERMANY

Mecklenburg-Vorpommern
ROSTOCK

Gastroenterology and hepatology clinic
Universitäts-Kinder- und Jugendklinik Rostock

GERMANY

Niedersachsen
HANNOVER

Hepatology clinic
Medizinische Hochschule Hannover

GERMANY

Niedersachsen
HANNOVER

Hepatology clinic
Medizinische Hochschule Hannover

GERMANY

Nordrhein-Westfalen
AACHEN

Gastroenterology and hepatology clinic
Universitätsklinikum Aachen

GERMANY

Nordrhein-Westfalen
AACHEN

Hepatology clinic
Universitätsklinikum Aachen

GERMANY

Nordrhein-Westfalen
BONN

Gastroenterology and hepatology clinic
Universitäts-Kinderklinik Bonn

GERMANY

Nordrhein-Westfalen
BONN

Gastroenterology and hepatology clinic
Universitätsklinikum Bonn

GERMANY

Nordrhein-Westfalen
DÜSSELDORF

Liver Centre Düsseldorf
Universitätsklinikum Düsseldorf

GERMANY

Nordrhein-Westfalen
ESSEN

Hepatology clinic
Universitätsklinikum Essen

GERMANY

Nordrhein-Westfalen
KREFELD

Gastroenterology and hepatology clinic
HELIOS Klinikum Krefeld

GERMANY

Nordrhein-Westfalen
MÜNSTER

Center for rare diseases in surgical orthopedic
Universitätsklinikum Münster

GERMANY

Nordrhein-Westfalen
MÜNSTER

Hepatology clinic
Universitätsklinikum Münster

GERMANY

Nordrhein-Westfalen
OBERHAUSEN

Hepatic diseases clinic
Katholischen Kliniken Oberhausen - St. Josef-Hospital

GERMANY

Rheinland-Pfalz
MAINZ

Hepatology clinic
Universitätsmedizin Mainz

GERMANY

Saarland
HOMBURG

Gastroenterology and hepatology clinic
Universitätsklinikum des Saarlandes

GERMANY

Sachsen
DRESDEN

Syndromic developmental disorders clinic
Universitätsklinikum Carl Gustav Carus an der TU Dresden

GERMANY

Sachsen
LEIPZIG

Hepatology clinic
Universitätsklinikum Leipzig AöR

GERMANY

Sachsen-Anhalt
HALLE (SAALE)

Liver and biliary diseases clinic
Universitätsklinikum Halle (Saale)

GERMANY

Schleswig-Holstein
KIEL

Hepatology clinic
Universitätsklinikum Schleswig-Holstein - Campus Kiel

GERMANY

Schleswig-Holstein
KIEL

Rare hepatic diseases clinic
Universitätsklinikum Schleswig-Holstein - Campus Kiel

GERMANY

Schleswig-Holstein
LÜBECK

Gastroenterology and hepatology clinic
Sana Kliniken Lübeck GmbH

GERMANY

Schleswig-Holstein
LÜBECK

Hepatic and biliary tract diseases clinic
Universitätsklinikum Schleswig-Holstein - Campus Lübeck

ITALY

LAZIO
ROMA

Centre of Expertise for rare pediatric addominal surgical diseases
IRCCS Ospedale Pediatrico Bambino Gesù - SEDE GIANICOLO

ITALY

LAZIO
ROMA

Specialized pediatric hepatology clinic
IRCCS Ospedale Pediatrico Bambino Gesù - SEDE GIANICOLO

ITALY

LIGURIA
GENOVA

Centre of Expertise for rare pediatric abdominal surgical diseases
IRCCS Istituto G. Gaslini - Ospedale Pediatrico

ITALY

LOMBARDIA
MILANO

Centre of Expertise for rare pediatric hepatic diseases
Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico

ITALY

LOMBARDIA
MILANO

Centre of Expertise for rare pediatric abdominal surgical diseases
Ospedale Maggiore Policlinico - Clinica Pediatrica De Marchi

ITALY

PUGLIA
SAN GIOVANNI ROTONDO

Centre of Expertise for rare pediatric hepatic diseases
IRCCS Ospedale Casa Sollievo della Sofferenza

ITALY

SICILIA
PALERMO

Centre of Expertise for rare pediatric hepatic diseases
ISMETT Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione

NETHERLANDS

Groningen
GRONINGEN

Centre for Familial Tumors
UMCG - Universitair Medisch Centrum Groningen

NETHERLANDS

Limburg
MAASTRICHT

Expertise Center Rare Syndromes and Cognitive Disorders
AZM - Academisch Ziekenhuis Maastricht

NETHERLANDS

Noord-Holland
AMSTERDAM

Very Rare and Unknown Syndromes Clinic
AMC - Academisch Medisch Centrum

SPAIN

Andalucía
MÁLAGA

Hepatology clinic
Hospital Regional Universitario de Málaga - Hospital Materno-Infantil

SPAIN

Madrid
MADRID

Prenatal diagnosis and genetic counseling in pregnancy
INGEMM - Instituto de Genética Médica y Molecular (IdiPAZ)

SWEDEN

Landstinget i Uppsala län
UPPSALA

Clinical Genetics
Akademiska Sjukhuset

SWEDEN

Stockholms läns landsting
STOCKHOLM

Clinical Genetics
Karolinska University Hospital - Clinical Genetics

SWITZERLAND

Suisse Alémanique
BERN

Oncogenetic clinic
Inselspital

SWITZERLAND

Suisse Romande
GENÈVE

Swiss Center for Liver Diseases in Children
Hôpital des Enfants - Hôpitaux Universitaires de Genève

SWITZERLAND

Suisse Romande
GENÈVE

Oncogenetics and cancer prevention unit
Hôpitaux Universitaires de Genève - Maternité

SWITZERLAND

Suisse Romande
LAUSANNE

Oncogenetic clinic
Hôpital Nestlé - CHUV

SWITZERLAND

Suisse Romande
SION

Oncogenetic clinic
Institut Central des Hôpitaux (ICH)

UNITED KINGDOM

Greater London
LONDON

UNITED KINGDOM

Greater Manchester
MANCHESTER

UNITED KINGDOM

West Midlands
BIRMINGHAM

Paediatric Liver Disease Treatment NHS Specialised Service
Birmingham Children's Hospital NHS Foundation Trust

BULGARIA

 South-West region
SOFIA

Dysmorphology clinic
University Hospital Alexandrovska

CYPRUS

Cyprus
NICOSIA

Dysmorphology clinic
Archbishop Makarios III hospital

DENMARK

Hovedstaden
COPENHAGEN

DENMARK

Jylland
AARHUS

Centre for rare diseases - CSS
Aarhus Universitetshospital - Skejby

ESTONIA

Tartu
TARTU

Dysmorphologic clinic
Tartu University Hospital

FRANCE

AUVERGNE-RHONE-ALPES
CLERMONT-FERRAND

FRANCE

AUVERGNE-RHONE-ALPES
GRENOBLE

FRANCE

AUVERGNE-RHONE-ALPES
SAINT-PRIEST-EN-JAREZ

FRANCE

BOURGOGNE-FRANCHE-COMTE
DIJON

FRANCE

BRETAGNE
VANNES

FRANCE

GRAND-EST
VANDOEUVRE-LÈS-NANCY

FRANCE

ILE-DE-FRANCE
BONDY

FRANCE

ILE-DE-FRANCE
CRÉTEIL

FRANCE

ILE-DE-FRANCE
PARIS

FRANCE

ILE-DE-FRANCE
PARIS

Reference centre for developmental anomalies and malformation syndromes IDF - Constitutive site
CHU Paris-GH La Pitié Salpêtrière-Charles Foix - Hôpital Pitié-Salpêtrière

FRANCE

ILE-DE-FRANCE
POISSY

Reference centre for developmental anomalies and malformation syndromes IDF - Constitutive site
Centre hospitalier intercommunal Poissy-Saint-Germain-en-Laye

FRANCE

OCCITANIE
TOULOUSE

FRANCE

OUTRE-MER
POINTE À PITRE

FRANCE

OUTRE-MER
SAINT-LAURENT-DU-MARONI

FRANCE

OUTRE-MER
SAINT-PIERRE

FRANCE

PROVENCE-ALPES-COTE D'AZUR
MARSEILLE

FRANCE

PROVENCE-ALPES-COTE D'AZUR
TOULON

GERMANY

Baden-Württemberg
FREIBURG

GERMANY

Baden-Württemberg
FREIBURG

Developmental defect during embryogenesis clinic
Zentrum für Kinder- und Jugendmedizin Freiburg

GERMANY

Baden-Württemberg
HEIDELBERG

Syndromic developmental disorders clinic
Universitätsmedizin Heidelberg

GERMANY

Mecklenburg-Vorpommern
GREIFSWALD

Congenital malformations clinic
Universitätsmedizin Greifswald

GERMANY

Niedersachsen
HANNOVER

Syndromology and dysmorphology clinic
Medizinische Hochschule Hannover

GERMANY

Nordrhein-Westfalen
AACHEN

Congenital malformations clinic
Universitätsklinikum Aachen

GERMANY

Nordrhein-Westfalen
AACHEN

Syndromology clinic
Universitätsklinikum Aachen

GERMANY

Nordrhein-Westfalen
ESSEN

Neuropediatrics clinic
Universitätsklinikum Essen

GERMANY

Nordrhein-Westfalen
ESSEN

Syndromology and dysmorphology clinic
Universitätsklinikum Essen

GERMANY

Schleswig-Holstein
LÜBECK

Developmental defect during embryogenesis clinic
Universitätsklinikum Schleswig-Holstein - Campus Lübeck

HUNGARY

Dél-Dunántúl
PECS

Dysmorphology clinic
Department of Paediatrics - Clinical Center - University of Pécs

ITALY

ABRUZZO
CHIETI

Centre of Expertise for dysmorphology
Policlinico Universitario di Chieti

ITALY

CALABRIA
CATANZARO

Dysmorphology clinic
Azienda Ospedaliera Pugliese Ciaccio

ITALY

CAMPANIA
AVELLINO

Centre of Expertise for dysmorphology
Azienda Ospedaliera San Giuseppe Moscati

ITALY

CAMPANIA
BENEVENTO

Centre of Expertise for dysmorphology
A.O.R.N. "Gaetano Rummo"

ITALY

CAMPANIA
NAPOLI

Centre of Expertise for dysmorphology
Azienda Ospedaliera "A. Cardarelli"

ITALY

CAMPANIA
NAPOLI

Centre of Expertise for dysmorphology
Azienda Ospedaliera Universitaria "Federico II"

ITALY

CAMPANIA
NAPOLI

Centre of Expertise for dysmorphology
Istituto di Genetica e Biofisica "Adriano Buzzati Traverso" - CNR

ITALY

CAMPANIA
SALERNO

Dysmorphology clinic
Centro Zigote S.r.L.

ITALY

EMILIA ROMAGNA
BOLOGNA

Centre of Expertise for rare developmental defect during embryogenesis
Policlinico S. Orsola-Malpighi - Area S. Orsola

ITALY

EMILIA ROMAGNA
IMOLA

ITALY

EMILIA ROMAGNA
PIEVESESTINA DI CESENA

Dysmorphologic clinic
AUSL Cesena

ITALY

EMILIA ROMAGNA
REGGIO EMILIA

Centre of Expertise for dysmorphology
IRCCS Arcispedale Santa Maria Nuova

ITALY

FRIULI VENEZIA GIULIA
TRIESTE

Dysmorphology clinic
IRCCS Burlo Garofolo - Istituto per l'Infanzia

ITALY

FRIULI VENEZIA GIULIA
UDINE

Regional Centre of Expertise for developmental anomalies and malformation syndromes (Williams syndrome)
Azienda Ospedaliero-Universitaria "Santa Maria della Misericordia" di Udine

ITALY

LAZIO
ROMA

Dysmorphology clinic
Azienda Ospedaliera S. Camillo-Forlanini - Ospedale San Camillo

ITALY

LAZIO
ROMA

Centre of Expertise for dysmorphology
IRCCS Ospedale Pediatrico Bambino Gesù - SEDE GIANICOLO

ITALY

LAZIO
ROMA

Dysmorphology clinic
IRCCS Ospedale Pediatrico Bambino Gesù - SEDE GIANICOLO

ITALY

LAZIO
ROMA

Dysmorphology clinic
Policlinico Umberto I

ITALY

LAZIO
ROMA

Dysmorphology clinic
Policlinico Universitario "A. Gemelli"

ITALY

LIGURIA
GENOVA

ITALY

LOMBARDIA
MILANO

Centre of Expertise for dysmorphology
Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico

ITALY

LOMBARDIA
MILANO

Centre of Expertise for dysmorphology
Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico

ITALY

LOMBARDIA
MILANO

Dysmorphology clinic
IRCCS Ospedale San Raffaele

ITALY

LOMBARDIA
MILANO

Centre of Expertise for dysmorphology
Ospedale Maggiore Policlinico - Clinica Pediatrica De Marchi

ITALY

LOMBARDIA
MILANO

Centre of Expertise for dysmorphology
Ospedale Niguarda Ca' Granda

ITALY

LOMBARDIA
MONZA

Centre of Expertise for dysmorphology
Azienda Ospedaliera San Gerardo

ITALY

MOLISE
CAMPOBASSO

Centre of Expertise for dysmorphology
Ospedale "Cardarelli" - ASReM - Zona di Campobasso

ITALY

PIEMONTE
TORINO

Centre of Expertise for dysmorphology
A.O. Città della Salute e della Scienza di Torino - Ospedale Regina Margherita

ITALY

PIEMONTE
VERBANIA

Dysmorphology clinic
Azienda Sanitaria Locale Verbano Cusio Ossola - Ospedale Castelli

ITALY

PUGLIA
ACQUAVIVA DELLE FONTI

Dysmorphology clinic
Ospedale F. Miulli

ITALY

PUGLIA
SAN GIOVANNI ROTONDO

Centre of Expertise for dysmorphology
IRCCS Ospedale Casa Sollievo della Sofferenza - Polamb. Giovanni Paolo II

ITALY

SARDEGNA
CAGLIARI

Dysmorphology clinic
Ospedale Regionale per le Microcitemie

ITALY

SICILIA
CATANIA

Centre of Expertise for congenital malformative syndromes
Azienda Ospedaliero Universitaria "Policlinico Vittorio Emanuele"

ITALY

SICILIA
CATANIA

Centre of Expertise for dysmorphology
Presidio Ospedaliero Garibaldi-Nesima

ITALY

SICILIA
PALERMO

Centre of Expertise for dysmorphology
Azienda Ospedaliera Ospedali Riuniti "Villa Sofia-Cervello" - Presidio Cervello

ITALY

SICILIA
PALERMO

Centre of Expertise for rare developmental defect during embryogenesis
Azienda Ospedaliera Ospedali Riuniti "Villa Sofia-Cervello" - Presidio Cervello

ITALY

SICILIA
PALERMO

Centre of Expertise for dysmorphology
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone"

ITALY

SICILIA
RAGUSA

Dysmorphology clinic
Azienda Sanitaria Provinciale di Ragusa

ITALY

SICILIA
TROINA

Centre of Expertise for dysmorphology
IRCCS OASI Maria Santissima

ITALY

TOSCANA
FIRENZE

Dysmorphology clinic
Azienda Ospedaliera Universitaria Anna Meyer

ITALY

TOSCANA
FIRENZE

Dysmorphology clinic
Azienda Ospedaliero Universitaria Careggi - NEUROFARBA

ITALY

TOSCANA
PISA

Dysmorphology specialized clinic
Azienda Ospedaliero Universitaria Pisana - Ospedale S. Chiara

ITALY

TOSCANA
SIENA

Dysmorphology clinic
Azienda Ospedaliera Universitaria Senese - Ospedale Santa Maria alle Scotte

ITALY

TOSCANA
SIENA

Dysmorphology clinic
Azienda Ospedaliera Universitaria Senese - Ospedale Santa Maria alle Scotte

ITALY

TOSCANA
SIENA

Centre of Expertise for Dysmorphology
Azienda Ospedaliera Universitaria Senese - Ospedale Santa Maria alle Scotte

ITALY

TRENTINO ALTO ADIGE
TRENTO

Centre of Expertise for dysmorphology
A.P.S.S. Provincia Autonoma di Trento

ITALY

UMBRIA
PERUGIA

Centre of Expertise for dysmorphology
Azienda Ospedaliera Universitaria di Perugia Santa Maria della Misericordia

ITALY

VENETO
BELLUNO

Dysmorphology clinic
Ospedale San Martino

ITALY

VENETO
DOLO

Dysmorphology clinic
Ospedale di Dolo - ULSS 13

ITALY

VENETO
PADOVA

Centre of Expertise for dysmorphology
Azienda Ospedaliera di Padova

LATVIA

LATVIA
RIGA

Dysmorphology clinic
Childrens University Hospital

LEBANON

Beyrouth
BEIRUT

Dysmorphology clinic
Université Saint-Joseph

LITHUANIA

DZUKIJA
VILNIUS

Dysmorphology clinic
Vilnius University Hospital Santariskiu Klinikos

MOROCCO

Fes
FES

Dysmorphology clinic
CENTRE HOSPITALIER UNIVERSITAIRE HASSAN II  

NETHERLANDS

Noord-Holland
AMSTERDAM

Dysmorphology Clinic
AMC - Academisch Medisch Centrum

NORWAY

Østlandet
OSLO

Dysmorphologic clinic
Oslo Universitetssykehus HF, Rikshospitalet

PORTUGAL

CENTRO
COIMBRA

Dysmorphology clinic
Centro Hospitalar e Universitário de Coimbra

PORTUGAL

NORTE
PORTO

Dysmorphology clinic
CGMJM - Centro de Genética Médica Jacinto Magalhães

PORTUGAL

NORTE
PORTO

Unit of Developmental and Perinatal disorders
Centro Hospitalar de S. João, EPE

PORTUGAL

NORTE
VILA REAL

Dysmorphology clinic
Centro Hospitalar de Vila Real-Peso da Régua, SA

PORTUGAL

SUL
LISBOA

Dysmorphology clinic
Hospital de Sta. Maria - Centro Hospitalar de Lisboa Norte, EPE.

ROMANIA

SIBIU
SIBIU

Dysmorphology clinic
Spitalul de Pediatrie Sibiu

SLOVENIA

SLOVENIA
LJUBLJANA

Dysmorphology clinic
University Medical Center Ljubljana

SPAIN

Cataluña
BARCELONA

Clinical genetics and dysmorphology clinic
Hospital Universitari Vall d'Hebron - Area Materno Infantil

SPAIN

Extremadura
BADAJOZ

Dysmorphology clinic
Hospital Infanta Cristina

SPAIN

Extremadura
CÁCERES

Dysmorphology pediatric clinic
Hospital San Pedro de Alcántara

SPAIN

Madrid
MADRID

Rare neoplastic diseases clinic
Fundación Jiménez Díaz

SPAIN

Madrid
MADRID

Dysmorphology clinic
Hospital Universitario 12 de Octubre

SPAIN

Murcia
EL PALMAR, MURCIA

Clinical genetics and dysmorphology clinic
Hospital Clínico Universitario Virgen de la Arrixaca

TURKEY

TURKEY
ANKARA

Dysmorphology clinic
Intergen Genetics Center

TURKEY

TURKEY
ISTANBUL

Dysmorpholgy clinic
Istanbul Universitesi, Tip Fakültesi