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Caption : Designated centres of expertise = Accreditation
Member of an ERN = ERN

BULGARIA

 North-East region
VARNA

FRANCE

HAUTS-DE-FRANCE
AMIENS

Competence centre for rare hepatic diseases
CHU d'Amiens - Hôpital Nord

FRANCE

ILE-DE-FRANCE
CLAMART

FRANCE

ILE-DE-FRANCE
LE KREMLIN-BICÊTRE

GERMANY

Bayern
MÜNCHEN

Hepatology clinic
Klinikum rechts der Isar der Technischen Universität München

GERMANY

Nordrhein-Westfalen
WUPPERTAL

Chronic inflammatory liver diseases clinic
HELIOS Universitätsklinikum Wuppertal - Universität Witten/Herdecke

GERMANY

Rheinland-Pfalz
MAINZ

Gastroenterology and hepatology clinic
Universitätsmedizin Mainz

UNITED KINGDOM

West Yorkshire
LEEDS

AUSTRIA

STEIERMARK
GRAZ

Gastroenterology and hepatology clinic
Medizinische Universität Graz

AUSTRIA

TIROL
INNSBRUCK

Pediatric gastroenterology and hepatology
Medizinische Universität Innsbruck

FRANCE

ILE-DE-FRANCE
PARIS

GERMANY

Baden-Württemberg
ESSLINGEN

Hepatology clinic
Klinikum Esslingen

GERMANY

Baden-Württemberg
FREIBURG

Hepatology clinic
Universitätsklinikum Freiburg

GERMANY

Baden-Württemberg
TÜBINGEN

Hepatology clinic
Behandlungs- und Forschungszentrum für Seltene Erkrankungen ZSE Tübingen

GERMANY

Baden-Württemberg
TÜBINGEN

Hepatic and biliary tract diseases clinic
Department für Innere Medizin - Medizinische Universitätsklinik Tübingen

GERMANY

Bayern
BAMBERG

GERMANY

Bayern
BAMBERG

Hepatology clinic
Klinikum Bamberg

GERMANY

Bayern
ERLANGEN

Hepatology clinic
Internistisches Zentrum des Universitätsklinikums Erlangen

GERMANY

Bayern
ERLANGEN

Gastroenterology and hepatology clinic
Kinder- und Jugendklinik des Universitätsklinikums Erlangen

GERMANY

Bayern
MÜNCHEN

Care-for-Rare Center (CRCHauner): specialised clinic for children with rare diseases
Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital

GERMANY

Bayern
MÜNCHEN

Hepatology clinic
Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital

GERMANY

Berlin
BERLIN

Hepatology clinic
Charité - Universitätsmedizin Berlin (CVK)

GERMANY

Hamburg
HAMBURG

Gastroenterology and hepatology clinic
UKE - Universitätsklinikum Hamburg-Eppendorf

GERMANY

Hessen
FRANKFURT AM MAIN

Gastroenterology and hepatology clinic
Klinikum der Johann Wolfgang Goethe-Universität Frankfurt

GERMANY

Hessen
FRANKFURT AM MAIN

Interdisciplinary liver center
Klinikum der Johann Wolfgang Goethe-Universität Frankfurt

GERMANY

Mecklenburg-Vorpommern
ROSTOCK

Gastroenterology and hepatology clinic
Universitäts-Kinder- und Jugendklinik Rostock

GERMANY

Niedersachsen
HANNOVER

Hepatology clinic
Medizinische Hochschule Hannover

GERMANY

Niedersachsen
HANNOVER

Hepatology clinic
Medizinische Hochschule Hannover

GERMANY

Nordrhein-Westfalen
AACHEN

Gastroenterology and hepatology clinic
Universitätsklinikum Aachen

GERMANY

Nordrhein-Westfalen
AACHEN

Hepatology clinic
Universitätsklinikum Aachen

GERMANY

Nordrhein-Westfalen
BONN

Gastroenterology and hepatology clinic
Universitäts-Kinderklinik Bonn

GERMANY

Nordrhein-Westfalen
BONN

Gastroenterology and hepatology clinic
Universitätsklinikum Bonn

GERMANY

Nordrhein-Westfalen
DÜSSELDORF

Liver Centre Düsseldorf
Universitätsklinikum Düsseldorf

GERMANY

Nordrhein-Westfalen
ESSEN

Hepatology clinic
Universitätsklinikum Essen

GERMANY

Nordrhein-Westfalen
KREFELD

Gastroenterology and hepatology clinic
HELIOS Klinikum Krefeld

GERMANY

Nordrhein-Westfalen
MÜNSTER

Hepatology clinic
Universitätsklinikum Münster

GERMANY

Nordrhein-Westfalen
OBERHAUSEN

Hepatic diseases clinic
Katholischen Kliniken Oberhausen - St. Josef-Hospital

GERMANY

Rheinland-Pfalz
MAINZ

Hepatology clinic
Universitätsmedizin Mainz

GERMANY

Saarland
HOMBURG

Gastroenterology and hepatology clinic
Universitätsklinikum des Saarlandes

GERMANY

Sachsen
LEIPZIG

Hepatology clinic
Universitätsklinikum Leipzig AöR

GERMANY

Sachsen-Anhalt
HALLE (SAALE)

Liver and biliary diseases clinic
Universitätsklinikum Halle (Saale)

GERMANY

Schleswig-Holstein
KIEL

Hepatology clinic
Universitätsklinikum Schleswig-Holstein - Campus Kiel

GERMANY

Schleswig-Holstein
KIEL

Rare hepatic diseases clinic
Universitätsklinikum Schleswig-Holstein - Campus Kiel

GERMANY

Schleswig-Holstein
LÜBECK

Gastroenterology and hepatology clinic
Sana Kliniken Lübeck GmbH

GERMANY

Schleswig-Holstein
LÜBECK

Hepatic and biliary tract diseases clinic
Universitätsklinikum Schleswig-Holstein - Campus Lübeck

ITALY

LAZIO
ROMA

Specialized pediatric hepatology clinic
IRCCS Ospedale Pediatrico Bambino Gesù - SEDE GIANICOLO

ITALY

LIGURIA
GENOVA

Centre of Expertise for lysosomal and glycogen storage diseases
IRCCS Istituto G. Gaslini - Ospedale Pediatrico

ITALY

LOMBARDIA
MILANO

Centre of Expertise for rare pediatric hepatic diseases
Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico

ITALY

PUGLIA
SAN GIOVANNI ROTONDO

Centre of Expertise for rare pediatric hepatic diseases
IRCCS Ospedale Casa Sollievo della Sofferenza

ITALY

SICILIA
PALERMO

Centre of Expertise for rare pediatric hepatic diseases
ISMETT Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione

NETHERLANDS

Groningen
GRONINGEN

Expert Centre for Hepatic Glycogen Storage Diseases
UMCG - Universitair Medisch Centrum Groningen

SPAIN

Andalucía
MÁLAGA

Hepatology clinic
Hospital Regional Universitario de Málaga - Hospital Materno-Infantil

SWITZERLAND

Suisse Romande
GENÈVE

Swiss Center for Liver Diseases in Children
Hôpital des Enfants - Hôpitaux Universitaires de Genève

UNITED KINGDOM

Greater London
LONDON

UNITED KINGDOM

West Midlands
BIRMINGHAM

Paediatric Liver Disease Treatment NHS Specialised Service
Birmingham Children's Hospital NHS Foundation Trust

CANADA

Manitoba
WINNIPEG

Genetics and Metabolism
Health Sciences Centre

CANADA

Ontario
MISSISSAUGA

Clinical Genetics, Credit Valley Site, Trillium Health Partners
Genetics Clinic, Credit Valley Hospital

CANADA

Ontario
TORONTO

Clinical and Metabolic Genetics Division
The Hospital for Sick Children and University of Toronto

CANADA

Québec
MONTRÉAL

Genetique Medicale
Centre hospitalier universitaire Sainte-Justine

CANADA

Québec
MONTRÉAL

Medical genetics pediatric clinic
Glen / McGill Univeristy Health Centre - Centre Universitaire de santé McGill

CANADA

Québec
MONTRÉAL

Medical genetics adult clinic
Glen / McGill Univeristy Health Centre - Centre Universitaire de santé McGill

CANADA

Québec
SHERBROOKE

Medical genetics service
CHU Sherbrooke - Hôpital Fleurimont

GERMANY

Berlin
BERLIN

Rare paediatric metabolic diseases clinic
Charité - Universitätsmedizin Berlin (CVK)

ITALY

LOMBARDIA
MANTOVA

ITALY

LOMBARDIA
MONZA

Centre of Expertise for inborn errors of metabolism
Azienda Ospedaliera San Gerardo

ITALY

LOMBARDIA
PAVIA

Centre of Expertise for the disorders of carbohydrate metabolism
Fondazione Istituto Neurologico "C. Mondino" - IRCCS

ITALY

PIEMONTE
TORINO

Centre of Expertise for inborn errors of metabolism
A.O. Città della Salute e della Scienza di Torino - Ospedale Regina Margherita

ITALY

SICILIA
PALERMO

Centre of Expertise for metabolic diseases
A.O. Civico - Di Cristina - Benfratelli

SPAIN

Madrid
MADRID

Prenatal diagnosis and genetic counseling in pregnancy
INGEMM - Instituto de Genética Médica y Molecular (IdiPAZ)

SWEDEN

Landstinget i Uppsala län
UPPSALA

Clinical Genetics
Akademiska Sjukhuset

SWEDEN

Stockholms läns landsting
STOCKHOLM

Clinical Genetics
Karolinska University Hospital - Clinical Genetics

UNITED KINGDOM

Greater Manchester
MANCHESTER

AUSTRIA

SALZBURG
SALZBURG

Outpatient clinic for inborn errors of metabolism
Salzburger Landeskliniken (SALK) / Paracelsus Med. Privatuniversität (PMU)

AUSTRIA

TIROL
INNSBRUCK

AUSTRIA

VORARLBERG
BREGENZ

BELGIUM

ANTWERPEN
ANTWERPEN-EDEGEM

Centre of Inherited Metabolic Diseases
University and University Hospital of Antwerp - UZA

BELGIUM

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS

Reference Centre Hereditary Metabolic Diseases - UCL StLuc
Cliniques Universitaires UCL de Saint Luc - UCLStLuc

BELGIUM

ARRONDISSEMENT BRUSSELS-CAPITAL
BRUSSELS

Reference Centre Hereditary Metabolic diseases - HUDERF
Hôpital Universitaire des Enfants Reine Fabiola - HUDERF

BELGIUM

HAINAUT
GOSSELIES

Reference Centre Hereditary Metabolic Diseases - IPG
Institut de Pathologie et de Génétique - Gosselies

BELGIUM

VLAAMS BRABANT
LEUVEN

BULGARIA

 South Central region
PLOVDIV

Medical Center UNIQUE
Medical Center 'UNIQUE'

BULGARIA

 South Central region
PLOVDIV

Medical Center RareDis
Medical Centre Raredis

BULGARIA

 South Central region
PLOVDIV

Clinic of pediatrics and genetic disorders
University Hospital Plovdiv - UMHAT Sv. Georgi - EAD

BULGARIA

 South-West region
SOFIA

Metabolic diseases specialised clinic
University Children's Hospital

CANADA

Québec
MONTRÉAL

Medical genetics metabolic clinic (pediatric and adult)
Glen / McGill Univeristy Health Centre - Centre Universitaire de santé McGill

DENMARK

Hovedstaden
COPENHAGEN

FRANCE

AUVERGNE-RHONE-ALPES
BRON

FRANCE

BOURGOGNE-FRANCHE-COMTE
BESANÇON

FRANCE

BOURGOGNE-FRANCHE-COMTE
DIJON

FRANCE

BOURGOGNE-FRANCHE-COMTE
DIJON

Reference centre for inherited metabolism diseases - Competence centre (children)
CHU Dijon Bourgogne - Hôpital François Mitterrand, Hôp. d'Enfants et Maternité

FRANCE

BRETAGNE
BREST

Competence centre for inherited metabolic diseases
CHRU de Brest - Hôpital Morvan

FRANCE

BRETAGNE
RENNES

FRANCE

CENTRE-VAL DE LOIRE
TOURS

FRANCE

GRAND-EST
STRASBOURG

FRANCE

GRAND-EST
VANDOEUVRE-LÈS-NANCY

FRANCE

HAUTS-DE-FRANCE
LILLE

FRANCE

HAUTS-DE-FRANCE
LILLE

FRANCE

ILE-DE-FRANCE
PARIS

Reference centre for inherited metabolic diseases - Constitutive site
CHU Paris - Hôpital Necker-Enfants Malades

FRANCE

ILE-DE-FRANCE
PARIS

FRANCE

ILE-DE-FRANCE
PARIS

FRANCE

ILE-DE-FRANCE
PARIS

FRANCE

ILE-DE-FRANCE
PARIS

FRANCE

NOUVELLE AQUITAINE
POITIERS

FRANCE

OCCITANIE
MONTPELLIER

Competence centre for inherited metabolic diseases
CHRU de Montpellier - Hôpital Gui de Chauliac

FRANCE

OCCITANIE
TOULOUSE

FRANCE

PAYS DE LA LOIRE
ANGERS

FRANCE

PROVENCE-ALPES-COTE D'AZUR
MARSEILLE

GERMANY

Baden-Württemberg
FREIBURG

Rare metabolic diseases clinic
Universitätsklinikum Freiburg

GERMANY

Baden-Württemberg
HEIDELBERG

Metabolic diseases clinic
Universitätsmedizin Heidelberg

GERMANY

Baden-Württemberg
REUTLINGEN

Congenital metabolic diseases clinic
Klinikum am Steinenberg

GERMANY

Baden-Württemberg
ULM

Metabolic diseases clinic
Klinik für Kinder- und Jugendmedizin des Universitätsklinikums Ulm

GERMANY

Baden-Württemberg
ULM

Metabolic diseases clinic
Universitätsklinikum Ulm am Oberen Eselsberg

GERMANY

Bayern
ERLANGEN

Congenital metabolic diseases clinic
Kinder- und Jugendklinik des Universitätsklinikums Erlangen

GERMANY

Bayern
MÜNCHEN

Metabolic diseases clinic
Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital

GERMANY

Bayern
MÜNCHEN

Metabolic diseases clinic
LMU Klinikum der Universität München - Campus Großhadern

GERMANY

Berlin
BERLIN

Metabolic diseases clinic
Charité - Universitätsmedizin Berlin (CVK)

GERMANY

Bremen
BREMEN

Metabolic disease clinic
Klinikum Bremen-Mitte

GERMANY

Hamburg
HAMBURG

Metabolic diseases clinic
UKE - Universitätsklinikum Hamburg-Eppendorf

GERMANY

Hessen
FRANKFURT AM MAIN

Metabolic diseases clinic
Klinikum der Johann Wolfgang Goethe-Universität Frankfurt

GERMANY

Hessen
GELNHAUSEN

GERMANY

Mecklenburg-Vorpommern
ROSTOCK

Metabolic diseases clinic
Universitäts-Kinder- und Jugendklinik Rostock

GERMANY

Niedersachsen
AURICH

Metabolic diseases clinic
Ubbo-Emmius-Klinik gGmbH

GERMANY

Niedersachsen
BRAUNSCHWEIG

Metabolic diseases clinic
Städtisches Klinikum Braunschweig - Standort Holwedestraße

GERMANY

Niedersachsen
HANNOVER

Metabolic diseases clinic
Endokrinologikum Hannover

GERMANY

Niedersachsen
HANNOVER

Metabolic diseases clinic
Medizinische Hochschule Hannover

GERMANY

Niedersachsen
OLDENBURG

Congenital metabolic diseases clinic
Klinikum Oldenburg gGmbH

GERMANY

Nordrhein-Westfalen
BOCHUM

Congenital metabolic diseases clinic
Klinik für Kinder- und Jugendmedizin im St. Josef-Hospital

GERMANY

Nordrhein-Westfalen
DÜSSELDORF

Metabolic diseases clinic
Universitätsklinikum Düsseldorf

GERMANY

Nordrhein-Westfalen
DÜSSELDORF

Metabolic diseases clinic
Universitätsklinikum Düsseldorf

GERMANY

Nordrhein-Westfalen
MÜNSTER

Congenital metabolic diseases clinic
Universitätsklinikum Münster

GERMANY

Rheinland-Pfalz
MAINZ

Metabolic and lysosomal diseases clinic
Universitätsmedizin Mainz

GERMANY

Sachsen
DRESDEN

Metabolic diseases clinic
Universitätsklinikum Carl Gustav Carus an der TU Dresden

GERMANY

Sachsen
LEIPZIG

Metabolic diseases clinic
Zentrum für Seltene Erkrankungen Leipzig

GERMANY

Sachsen
LEIPZIG

Congenital metabolic diseases clinic
Zentrum für Seltene Erkrankungen Leipzig

GERMANY

Sachsen-Anhalt
MAGDEBURG

Metabolic diseases clinic
Universitätsklinikum Magdeburg A.ö.R

GERMANY

Thüringen
JENA

IRELAND

County Dublin
DUBLIN

Inborn Errors of Metabolism clinic
Children's University Hospital

IRELAND

County Dublin
DUBLIN

Inborn Errors of Metabolism Clinic
Mater Misericordiae Hospital

ISRAEL

ISRAEL
AFULA

Metabolic diseases consultation
Emek Medical Center

ITALY

CAMPANIA
NAPOLI

Centre of Expertise for inborn errors of metabolism
Azienda Ospedaliera Universitaria "Federico II"

ITALY

CAMPANIA
NAPOLI

Centre of Expertise for inborn errors of metabolism
Azienda Ospedaliera Universitaria "Federico II"

ITALY

CAMPANIA
NAPOLI

Centre of Expertise for inborn errors of metabolism
Azienda Ospedaliera Universitaria - Seconda Università degli Studi di Napoli

ITALY

EMILIA ROMAGNA
PIACENZA

Centre of Expertise for pediatric hereditary metabolic diseases
Ospedale Guglielmo da Saliceto - AUSL Piacenza

ITALY

LAZIO
ROMA

Centre of expertise for metabolic diseases
IRCCS Ospedale Pediatrico Bambino Gesù

ITALY

LIGURIA
GENOVA

Centre of Expertise for inborn errors of metabolism
IRCCS Istituto G. Gaslini - Ospedale Pediatrico

ITALY

PUGLIA
BARI

Centre of Expertise for inborn errors of metabolism
Ospedale Pediatrico Giovanni XXIII

ITALY

SARDEGNA
CAGLIARI

Metabolic diseases specialized clinic
Ospedale Regionale per le Microcitemie

ITALY

SICILIA
CATANIA

Centre of Expertise for inborn errors of metabolism
Azienda Ospedaliero Universitaria "Policlinico Vittorio Emanuele"

ITALY

TOSCANA
FIRENZE

Centre of Expertise for inborn errors of metabolism
Azienda Ospedaliera Universitaria Anna Meyer

ITALY

VENETO
BASSANO DEL GRAPPA

ITALY

VENETO
PADOVA

Centre of Expertise for metabolic diseases
Azienda Ospedaliera di Padova

ITALY

VENETO
VERONA

Inborn errors of metabolism specialized clinic
Azienda Ospedaliera Universitaria Integrata di Verona - Ospedale Borgo Roma

MOROCCO

Casablanca
CASABLANCA

NETHERLANDS

Noord-Holland
AMSTERDAM

Metabolic Diseases Clinic
AMC - Academisch Medisch Centrum

NETHERLANDS

Noord-Holland
AMSTERDAM

Pediatric Metabolic Diseases Clinic
AMC - Academisch Medisch Centrum

NETHERLANDS

Utrecht
UTRECHT

Pediatric Metabolic Diseases Clinic
UMC Utrecht - Universitair Medisch Centrum Utrecht

NETHERLANDS

Zuid-Holland
ROTTERDAM

Metabolic Diseases Clinic
Erasmus MC - Erasmus Medisch Centrum

POLAND

Warszawa
WARSAW

Clinic for metabolic diseases
Instytut "Pomnik-Centrum Zdrowia Dziecka"

PORTUGAL

CENTRO
COIMBRA

Metabolic diseases clinic
Centro Hospitalar e Universitário de Coimbra

PORTUGAL

NORTE
PORTO

Pediatric metabolic disorder unit
Centro Hospitalar de S. João, EPE

PORTUGAL

NORTE
PORTO

Metabolic diseases clinic
Centro Materno Infantil do Centro Hospitalar do Porto

PORTUGAL

SUL
LISBOA

Metabolic diseases clinic
Hospital Dona Estefânia - Centro Hospitalar de Lisboa Central - EPE

PORTUGAL

SUL
LISBOA

Adult metabolic diseases outpatient clinic
Hospital de Sta. Maria - Centro Hospitalar de Lisboa Norte, EPE.

PORTUGAL

SUL
LISBOA

Inborn Errors of Metabolism Unit
Hospital de Sta. Maria - Centro Hospitalar de Lisboa Norte, EPE.

ROMANIA

IASI
IASI

Pediatric service : gastroenterology and metabolism
Spitalul Clinic de Urgente pentru Copii Sfanta Maria

SLOVAKIA

Bratislavsky kraj
BRATISLAVA

Center for Inherited Metabolic Diseases
DFNsP - University Children´s Hospital

SPAIN

Andalucía
MÁLAGA

Metabolic disorders clinic
Hospital Regional Universitario de Málaga - Hospital Materno-Infantil

SPAIN

Aragón
ZARAGOZA

Hereditary metabolic diseases clinic
Hospital Universitario Miguel Servet

SPAIN

Cataluña
BARCELONA

CSUR - National centre of expertise for congenital metabolic diseases
Hospital Universitari General Vall d'Hebron

SPAIN

Cataluña
ESPLUGUES DE LLOBREGAT

SPAIN

Comunidad Valenciana
VALENCIA

CSUR - National centre of expertise for congenital metabolic diseases
Hospital Universitario y Politécnico La Fe

SPAIN

Galicia
SANTIAGO DE COMPOSTELA

CSUR - National centre of expertise for congenital metabolic diseases
CHUS - Complejo Hospitalario Universitario de Santiago

SPAIN

Madrid
MADRID

SPAIN

País Vasco
BARAKALDO

SWITZERLAND

Suisse Alémanique
ST. GALLEN

Pediatric Metabolic diseases Clinic
Ostschweizer Kinderspital

SWITZERLAND

Suisse Alémanique
ZÜRICH

Metabolic diseases clinic
Universitäts - Kinderspital Zürich - Eleonorenstiftung

SWITZERLAND

Suisse Alémanique
ZÜRICH

Rare metabolic diseases clinic
UniversitätsSpital Zürich

SWITZERLAND

Suisse Romande
GENÈVE

Paediatric metabolic diseases clinic
Hôpital des Enfants - Hôpitaux Universitaires de Genève

SWITZERLAND

Suisse Romande
GENÈVE

Adult clinic of inborn errors of metabolism
Hôpitaux Universitaires de Genève HUG

SWITZERLAND

Suisse Romande
LAUSANNE

Metabolic and molecular diseases clinic for children and adult
Centre Hospitalier Universitaire Vaudois CHUV

TURKEY

TURKEY
ANKARA

Inborn Errors of Metabolism clinic
Hacettepe University Faculty of Medicine

UNITED KINGDOM

Greater London
LONDON

Charles Dent Metabolic Unit
National Hospital for Neurology and Neurosurgery

UNITED KINGDOM

Greater Manchester
SALFORD

The Mark Holland Metabolic Unit
The Mark Holland Metabolic Unit

UNITED KINGDOM

South Glamorgan
CARDIFF

Cardiff Inherited Metabolic Disease Service
Cardiff & Vale University Health Board