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APP - amyloid beta precursor protein

Synonym(s) : peptidase nexin-II
Previous symbols and names : AD1, Alzheimer disease, amyloid beta (A4) precursor protein
Type : gene with protein product
Chromosomal location : 21q21.3
OMIM: 104760
HGNC: 620
UniProtKB: P05067
Genatlas: APP
Ensembl: ENSG00000142192
IUPHAR-DB: -
Reactome: P05067

Diseases list

Disease-causing germline mutation(s) in ABetaA21G amyloidosis
Disease-causing germline mutation(s) in ABeta amyloidosis, Arctic type
Disease-causing germline mutation(s) in ABeta amyloidosis, Dutch type
Disease-causing germline mutation(s) in ABeta amyloidosis, Iowa type
Disease-causing germline mutation(s) in ABeta amyloidosis, Italian type
Disease-causing germline mutation(s) in ABetaL34V amyloidosis
Disease-causing germline mutation(s) in Early-onset autosomal dominant Alzheimer disease

: Assessed

Additional information

Health care resources for this gene

Diagnostic tests (71)

Research activities on this gene

Specialised Social Services

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