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Buerger disease

Disease definition

Buerger disease, also known as thromboangiitis obliterans (TAO), is a rare inflammatory non-necrotizing vascular disease affecting the small- and medium-sized arteries and veins of the upper and lower extremities characterized by endarteritis and vaso-occlusion due to occlusive thrombus development. The development and progression of the disease is consistently associated with exposure to tobacco.

ORPHA:36258

  • Synonym(s):
    • Thromboangiitis obliterans
  • Prevalence: 1-5 / 10 000
  • Inheritance: -
  • Age of onset: Adult
  • ICD-10: I73.1
  • OMIM: 211480
  • UMLS: C0040021
  • MeSH: -
  • GARD: 5969
  • MedDRA: -

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