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Dense deposit disease

Orpha number ORPHA93571
Synonym(s) Membranoproliferative glomerulonephritis type 2
Prevalence 1-9 / 100 000
Inheritance Autosomal recessive
Age of onset Childhood
ICD-10 -
ICD-O -
OMIM
UMLS
  • C0268743
MeSH
  • D015432
MedDRA -
SNOMED CT
  • 59479006

Summary

Type 2 membranoproliferative glomerulonephritis (MPGN), a pathological subtype of MPGN (see this term) is an idiopathic chronic progressive kidney disorder distinguished by the presence of intra-membranous dense deposits in addition to immune complex subendothelial deposits in the glomerular capillary walls. This form often has a higher recurrence rate after a kidney transplant and is associated with extra-renal manifestations such as familial drusen (see this term).


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Detailed information

Clinical genetics review
  • EN (2011)
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