Orphanet: Syndrome d alpha thalassemie syndrome myelodysplasique

Search for a rare disease

* (*) mandatory field

Other search option(s)

Suggest an update

(*) Required fields.


Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Captcha image

Alpha-thalassemia-myelodysplastic syndrome

Disease definition

Alpha-thalassemia-myelodysplastic syndrome (ATMDS) is an acquired form of alpha-thalassemia (see this term) characterized by a myelodysplastic syndrome (MDS) or more rarely a myeloproliferative disease (MPD) associated with hemoglobin H disease (HbH; see these terms).


  • Synonym(s):
    • ATMDS
    • Acquired HbH disease
    • Acquired hemoglobin H disease
  • Prevalence: <1 / 1 000 000
  • Inheritance: Not applicable 
  • Age of onset: Adult
  • ICD-10: D46.7  D56.0
  • OMIM: 300448
  • UMLS: C0585216
  • MeSH: -
  • GARD: -
  • MedDRA: -

Detailed information


Additional information

Specialised Social Services

The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.