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Nephroblastoma

Disease definition

Nephroblastoma is the most frequent malignant renal tumor in children and is associated with an abnormal proliferation of cells that resemble the kidney cells of an embryo (metanephroma), leading to the term embryonal tumor.

ORPHA:654

  • Synonym(s):
    • Renal embryonic tumor
    • Wilms tumor
  • Prevalence: 1-9 / 100 000
  • Inheritance: Autosomal dominant or Not applicable 
  • Age of onset: Childhood
  • ICD-10: C64
  • OMIM: 194070  194071  194090  601363  601583  616806
  • UMLS: C0027708
  • MeSH: D009396
  • GARD: 7892
  • MedDRA: 10029145

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