Orphan Designations by geographical area
- Lamotrigine
- Lanreotide acetate
- Laronidase
- L-Asparaginase
- L-asparaginase encapsulated in erythrocytes
- Late Stage Human Motor Neutron Progenitors
- L carnitine
- L-cysteine, L-leucyl-L-alpha-glutamyl-L-alpha-glutamyl-L-lysyl-L-lysylglycyl-L-asparaginyl-L-tyrosyl-L-valyl-L-valyl-L-threonyl-L-alpha-aspartyl-L-histidyl-S-[1-[(4-carboxycyclohexyl)methyl]-2,5-dioxo-3-pyrrolidinyl]-complex with keyhole limpet haemocyanin
- Lenalidomide
- Lentiviral vector carrying the Fanconi anaemia-A (FANCA) gene
- Lentiviral vector containing the human ABCA4 gene
- Lentiviral vector containing the human MYO7A gene
- Lentiviral vector containing the human Wiskott Aldrich syndrome protein gene
- Lepirudin
- Lestaurtinib
- Letermovir
- Leukocyte interleukin
- Leuprolide acetate
- Levamisol hydrochloride
- Levodopa and Carbidopa (Gastroenteral use)
- Levofloxacin hemihydrate
- Levoglutamide
- Liarozole
- Lintuzumab
- Lipopolysaccharide of Ochrobactrum intermedium
- Liposomal combination of cytarabine and daunorubicin
- Liposomal daunorubicin
- Lisuride hydrogen maleate
- Lithium citrate tetrahydrate (in reverse-micelle formulation)
- L-Lysine-N-acetyl-L-cysteinate
- Lomitapide
- Low molecular weight dextran sulfate
- L-threo-3,4-dihydroxyphenylserine
- Lucinactant
- Lurbinectedin
- Lutetium (177Lu)-N-[(4,7,10-Tricarboxymethyl-1,4,7,10-tetraazacyclododec-1-yl)acetyl]-D-phenylalanyl- L-cysteinyl-L-tyrosyl-D-tryptophanyl-L-lysyl-L-threoninyl-L-cysteinyl-Lthreonine-cyclic(2-7)disulfide
