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White sponge nevus

Synonym(s) Hereditary mucosal leukokeratosis
White sponge nevus of Cannon
Prevalence -
Inheritance Autosomal dominant
Age of onset -
  • Q38.6
MeSH -
MedDRA -


Disease definition

White sponge nevus (WSN) is a rare and autosomal dominant genetic disease in which the oral mucosa is white or greyish, thickened, folded, and spongy. The onset is early in life, and both sexes are affected equally. Other common sites include the tongue, floor of the mouth, and alveolar mucosa.

Expert reviewer(s)

  • Dr Ségolène AYME

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