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Primary membranoproliferative glomerulonephritis

Orpha number ORPHA54370
Synonym(s) MPGN
Mesangiocapillary glomerulonephritis
Prevalence 1-5 / 10 000
Inheritance -
Age of onset -
ICD-10 -
ICD-O -
OMIM
UMLS
  • C0017662
MeSH
  • D015432
MedDRA
  • 10018370
SNOMED CT
  • 80321008

Summary

Membranoproliferative glomerulonephritis (MPGN) is a chronic progressive kidney disorder characterized by glomerular capillary wall structural changes and mesangial cell proliferation leading to nephrotic syndrome, hypocomplementemia, hypertension, proteinuria and end-stage kidney disease. MPGN can be due to either idiopathic (type 1, 2 and 3 MPGN; see these terms) or secondary (associated with infectious and immune complex diseases) causes.


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