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Squamous cell carcinoma of head and neck
Disease definition
Squamous cell carcinoma of head and neck (SCCHN) is a highly malignant neoplasm that can occur on the lip, oral cavity, nasal cavity, pharynx, larynx and paranasal sinuses and that accounts for 90% of all head and neck cancers, occurring most frequently in adults between the ages of 40-60. SCCHN presents with a variety of manifestations, depending on the primary site, such as voice hoarsness, dysphagia, ulceration of oral mucosa, hearing loss, epistaxis, nasal obstruction and enlargement of a cervical lymph node (neck secondaries) and is often associated with extensive invasion into surrounding tissues and a rapid metastasis to distant organs.
ORPHA:67037
- Synonym(s):
- HNSCC
- Head and neck squamous cell carcinoma
- Prevalence: 1-5 / 10 000
- Inheritance: Multigenic/multifactorial or Not applicable
- Age of onset: All ages
- ICD-10: -
- OMIM: 275355
- UMLS: C1168401
- MeSH: C535575
- GARD: -
- MedDRA: 10060121
Detailed information
Article for general public
Professionals
- Review article
- English (2015)
- Clinical practice guidelines
- English (2011)
Additional information
Further information on this disease
Health care resources for this disease
Research activities on this disease
Specialised Social Services
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