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TRAPS syndrome

Orpha number ORPHA32960
Synonym(s) Autosomal dominant periodic fever
Familial hibernian fever
TNF receptor 1 associated periodic syndrome
Tumor necrosis factor receptor 1 associated periodic syndrome
Prevalence Unknown
  • Autosomal dominant
Age of onset Childhood
  • E85.0
MeSH -
MedDRA -


TRAPS (Tumor necrosis receptor associated periodic fever syndrome) is an autosomal dominant periodic fever syndrome, characterized by severe recurrent fever, arthralgia, myalgia and tender skin lesions lasting for 1 to 3 weeks associated with skin, joint, ocular and serosal inflammation and complicated by AA amyloidosis.

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Detailed information

Summary information
Review article
  • FR (2008)
Guidance for genetic testing
  • EN (2012,pdf)
Article for general public
  • FR (2012)
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