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Multiple system atrophy

Disease definition

Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by autonomic failure (cardiovascular and/or urinary), parkinsonism, cerebellar impairment and corticospinal signs with a median survival of 6-9 years.

ORPHA:102

  • Synonym(s):
    • MSA
    • Multisystem atrophy
  • Prevalence: 1-9 / 100 000
  • Inheritance: Multigenic/multifactorial or Not applicable 
  • Age of onset: Adult
  • ICD-10: G90.3
  • OMIM: 146500
  • UMLS: C0393571
  • MeSH: D019578
  • GARD: 7079
  • MedDRA: 10064060

Detailed information

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