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Castleman disease

Disease definition

Castleman disease (CD) is a benign lymphoproliferative disorder that may present as a localized or multicentric form (see these terms). The clinical manifestations are heterogeneous, ranging from asymptomatic discrete lymphadenopathy to recurrent episodes of diffuse lymphadenopathy with severe systemic symptoms.

ORPHA:160

  • Synonym(s):
    • Angiofollicular ganglionic hyperplasia
    • Angiofollicular lymph hyperplasia
  • Prevalence: Unknown
  • Inheritance: Not applicable 
  • Age of onset: All ages
  • ICD-10: D47.4
  • OMIM: 148000
  • UMLS: C0017531  C2931179
  • MeSH: C536362  D005871
  • GARD: 12656
  • MedDRA: 10050251

Detailed information

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Additional information

Further information on this disease

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