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Sporadic Creutzfeldt-Jakob disease

Synonym(s) Sporadic CJD
Prevalence 1-9 / 1 000 000
Inheritance Not applicable
Age of onset Adult
  • A81.0
  • C0022336
  • D007562
  • 10011384


Disease definition

Sporadic Creutzfeldt-Jakob disease (sCJD) is a subacute fatal neurodegenerative disease belonging to the group of prion diseases, characterized by a clinical triad of dementia, myoclonus, and EEG anomalies, along with neuropathological evidence of neuronal loss, spongiform changes, and astrocytosis. There are three types of CJD: sporadicCJD (sCJD), inherited CJD (see this term), and iatrogenic and variant CJD (vCJD).

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Clinical practice guidelines
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