Orphanet: Ankylosing vertebral hyperostosis with tylosis

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Ankylosing vertebral hyperostosis with tylosis

Disease definition

This syndrome is characterized by the association of ankylosing vertebral hyperostosis with hyperkeratosis of the soles and palms.


  • Synonym(s): -
  • Prevalence: <1 / 1 000 000
  • Inheritance: Autosomal dominant 
  • Age of onset: Adult
  • ICD-10: M48.1
  • OMIM: 106400
  • UMLS: -
  • MeSH: -
  • GARD: 842
  • MedDRA: -

Additional information

Further information on this disease

Specialised Social Services

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