x

Search for a rare disease

* (*) mandatory field

Suggest an update

(*) Required fields.

Attention

Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Captcha image

Familial cerebral cavernous malformation

Disease definition

Familial cerebral cavernous malformation (FCCM) is a rare evolutive vascular malformation disorder characterized by closely clustered irregular dilated capillaries that can be asymptomatic or that can cause variable neurological manifestations such as seizures, non-specific headaches, progressive or transient focal neurologic deficits, and/or cerebral hemorrhages.

ORPHA:221061

  • Synonym(s):
    • Familial brain cavernous angioma
    • Familial brain cavernous hemangioma
    • Familial cerebral cavernoma
    • Hereditary brain cavernous angioma
    • Hereditary brain cavernous hemangioma
    • Hereditary cerebral cavernoma
    • Hereditary cerebral cavernous malformation
  • Prevalence: 1-5 / 10 000
  • Inheritance: Autosomal dominant 
  • Age of onset: All ages
  • ICD-10: Q28.3
  • OMIM: 116860  603284  603285
  • UMLS: C2931263
  • MeSH: -
  • GARD: -
  • MedDRA: -

Detailed information

Article for general public

Professionals

Additional information

Further information on this disease

Specialised Social Services

The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.