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Ménétrier disease

Disease definition

Ménétrier disease (MD) is a rare premalignant hyperproliferative gastropathy characterized by massive overgrowth of foveolar cells in the gastric lining, resulting in large gastric folds, and manifesting with epigastric pain, nausea, vomiting, peripheral edema and, less commonly, anorexia and weight loss.

ORPHA:2494

  • Synonym(s):
    • Giant hypertrophic gastritis
    • Hypoproteinemic hypertrophic gastropathy
  • Prevalence: Unknown
  • Inheritance: Unknown or Not applicable 
  • Age of onset: Childhood, Adolescent, Adult
  • ICD-10: K29.6
  • OMIM: 137280
  • UMLS: C0017155
  • MeSH: -
  • GARD: 2436
  • MedDRA: 10017807  10017868

Additional information

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