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Syndactyly type 8

Disease definition

Syndactyly type 8 is a rare, genetic, non-syndromic, congenital limb malformation characterized by unilateral or bilateral fusion of the fourth and fifth metacarpals with no other associated abnomalities. Patients present shortened fourth and fifth metacarpals with excessive separation between their distal ends, resulting in marked ulnar deviation of the little finger and an inability to bring the fifth finger in parallel with the other fingers.


  • Synonym(s):
    • Fusion of metacarpals 4 and 5
  • Prevalence: -
  • Inheritance: Autosomal dominant or X-linked recessive 
  • Age of onset: -
  • ICD-10: Q70.0
  • OMIM: 309630
  • UMLS: C1839728
  • MeSH: -
  • GARD: 3559
  • MedDRA: -

Additional information

Further information on this disease

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