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Eosinophilic fasciitis

Disease definition

Eosinophilic fasciitis is a rare connective tissue disease that is characterized by inflammation and thickening of the fascia, usually associated with peripheral eosinophilia. It presents during adulthood with symmetrical and painful swelling of mainly the extremities that progressively become indurated. Fatigue, disabling cutaneous fibrosis, myositis and arthritis may also be observed.

ORPHA:3165

  • Synonym(s):
    • Diffuse fasciitis with eosinophilia
    • Shulman syndrome
  • Prevalence: Unknown
  • Inheritance: Unknown 
  • Age of onset: Adult
  • ICD-10: M35.4
  • OMIM: 226350
  • UMLS: C0264005
  • MeSH: -
  • GARD: 6351
  • MedDRA: 10014954

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