Skip to
  1. Homepage
  2. Rare diseases
  3. Search
Simple search

Simple search

(*) mandatory field


Other search option(s)

Cerebroretinal vasculopathy

Synonym(s) CRV
Grand-Kaine-Fulling syndrome
Prevalence <1 / 1 000 000
Inheritance Autosomal dominant
Age of onset Adult
  • E75.2
MeSH -
MedDRA -


Disease definition

Cerebroretinal vasculopathy (CRV) is a phenotypic variant of a group of inherited small vessel disorders known as retinal vasculopathy and cerebral leukodystrophy (RVCL; see this term), characterized by strokes, vision loss, migraines, pseudotumours, dementia and occasionally renal disease.

(*) Required fields.

Attention: Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.

Captcha image

Detailed information

Summary information
Get Acrobat Reader
The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.