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Liddle syndrome

Disease definition

Liddle syndrome is a rare inherited form of hypertension characterized by severe early-onset hypertension associated with decreased plasmatic levels of potassium, renin and aldosterone.

ORPHA:526

  • Synonym(s):
    • Pseudoaldosteronism
    • Pseudohyperaldosteronism type 1
  • Prevalence: <1 / 1 000 000
  • Inheritance: Autosomal dominant 
  • Age of onset: Childhood
  • ICD-10: I15.1
  • OMIM: 177200
  • UMLS: C0221043
  • MeSH: D056929
  • GARD: 7381
  • MedDRA: 10037113  10052313

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