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Synonym(s) Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes
Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes
Prevalence Unknown
Inheritance Mitochondrial inheritance
or Not applicable
Age of onset Childhood
  • G71.3
  • C0162671
  • D017241
  • 10053872


MELAS (Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke) syndrome is a rare progressive multisystemic disorder characterized by encephalomyopathy, lactic acidosis, and stroke-like episodes. Other features include endocrinopathy, heart disease, diabetes, hearing loss, and neurological and psychiatric manifestations.

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