Skip to
  1. Homepage
  2. Rare diseases
  3. Search
Simple search

Simple search

*
(*) mandatory field





 

Other search option(s)

Gorham-Stout disease

Orpha number ORPHA73
Synonym(s) Diffuse cystic angiomatosis of bone
Essential osteolysis
Gorham disease
Gorham syndrome
Idiopathic massive osteolysis
Massive osteolysis
Phantom bone disease
Progressive massive osteolysis
Vanishing bone disease
Prevalence Unknown
Inheritance Not applicable
Age of onset All ages
ICD-10
  • M89.5
ICD-O -
OMIM
UMLS
  • C0029438
MeSH -
MedDRA
  • 10071283
SNOMED CT
  • 1515008

Summary

Gorham-Stout disease (GSD) is a congenital vascular bone disease causing massive osteolysis due to proliferation of vascular elements and osteoclasts. GSD may affect any bone in the body and can be monostotic or polyostotic. The most common symptom is localized pain. Other symptoms include swelling, weakness and functional impairment of affected limbs. The disease may be discovered after a pathological fracture.


(*) Required fields.

Attention: Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. For all other comments, please send your remarks via contact us. Only comments written in English can be processed.


Captcha image

Detailed information

Summary information
Get Acrobat Reader
The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.