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Autosomal dominant nail dysplasia

Orpha number ORPHA79153
Synonym(s) Onychodystrophy totalis
Twenty-nail dystrophy
Prevalence Unknown
Inheritance Autosomal dominant
Age of onset Childhood
ICD-10
  • L60.3
ICD-O -
OMIM
UMLS -
MeSH -
MedDRA -

Summary

Nail dysplasia is an idiopathic nail dystrophy, beginning in early childhood, and characterised by excessive longitudinal striations and loss of nail luster affecting all 20 nails. Few families have been described. Transmission is autosomal dominant. Histopathological analysis should exclude lichen planus or other skin diseases. The disorder progressively resolves.


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