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Apert syndrome

Orpha number ORPHA87
Synonym(s) ACS1
Acrocephalosyndactyly type 1
Prevalence 1-9 / 100 000
Inheritance Autosomal dominant
Age of onset Neonatal
  • Q87.0
  • C0001193
  • D000168
  • 10002943


Apert syndrome (AS) is a frequent form of acrocephalosyndactyly (see this term), a group of rare genetic syndromes, and is characterized by craniosynostosis, midface hypoplasia, and finger and toe syndactyly.

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Detailed information

Summary information
Anesthesia guidelines
  • EN (2011,pdf)
Clinical genetics review
  • EN (2011)
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