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Orpha number ORPHA97282
Synonym(s) Diarrheogenic islet cell tumor
Pancreatic cholera
VIP-secreting tumor
Verner-Morrison syndrome
WDHA syndrome
Watery diarrhea - hypokalemia - achlorhydria
Watery diarrhea - hypokalemic alkalosis
Prevalence -
Inheritance -
Age of onset -
  • E16.8
  • C0011993
  • D003969
  • 10047430


VIPoma is an extremely rare type of pancreatic neuroendocrine tumor (see this term) that secretes vasoactive intestinal polypeptide (VIP) leading to the manifestations of watery diarrhea, hypokalemia and achlorhydia or hypochhlorhydia (known as WDHA syndrome).

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Detailed information

Clinical practice guidelines
  • EN (2012)
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