Orphanet: Spinocerebellar ataxia type 21

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Spinocerebellar ataxia type 21

Disease definition

Spinocerebellar ataxia type 21 (SCA21) is a very rare subtype of type I autosomal dominant cerebellar ataxia (ADCA type I; see this term). It is characterized by slowly progressive cerebellar ataxia, mild cognitive impairment, postural and/or resting tremor, bradykinesia, and rigidity.


  • Synonym(s):
    • SCA21
  • Prevalence: <1 / 1 000 000
  • Inheritance: Autosomal dominant 
  • Age of onset: Adolescent
  • ICD-10: G11.1
  • OMIM: 607454
  • UMLS: C1843891
  • MeSH: C537200
  • GARD: 9999
  • MedDRA: -

Detailed information

Article for general public


Additional information

Further information on this disease

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