Orphan Designations by geographical area
- Dantrolene sodium
- Darinaparsin
- Dasatinib
- Daunorubicin (liposomal)
- Daunorubicin liposome injection
- Davunetide
- Decitabine
- Deferasirox
- Deferiprone
- Deferoxamine mesilate
- Defibrotide
- Deforolimus
- Denileukin diftitox
- Denufosol tetrasodium
- Deoxyribose phosphorothioate (5´-tct-ccc-agc-gtg-cgc-cat-3´)
- Desipramine chlorhydrate
- Desmoglein 3 synthetic peptide
- Desmopressine acetate
- Dexamethasone (40 mg tablet)
- Dexamethasone (intravitreal implant)
- Dexamethasone phosphate (iontophoretic solution, ocular use)
- Dexamethasone sodium phosphate encapsulated in human erythrocytes
- Dexrazoxane
- Digoxin immune FAB (Ovine)
- Dimethyl sulfoxide
- Dinaciclib
- Dipalmitoylphosphatidylcholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol, sodium salt, synthetic surfactant protein C analogue and synthetic surfactant protein B analogue
- Diphenylcyclopropenone
- Donor lymphocyte preparation depleted of functional alloreactive T-cells
- Dornase alfa
- Doxorubicin (administered after synthetic double-stranded siRNA oligonucleotide directed against claudin-5 complexed with polyethyleneimine)
- Doxorubicin hydrochloride (drug eluting beads)
- Doxorubicin hydrochloride (in heat-sensitive liposomes)
- Doxorubicin hydrochloride (liposomal)
- Doxorubicin hydrochloride (pegylated liposomal)
- Doxorubicin polyisohexylcyanoacrylate nanoparticles
- Doxycycline hyclate
- Drotrecogin alfa (activated)
- Dry extract from Birch bark (DER 0.1-0.2:1), extraction solvent n-heptane 95% (V/V)
- Duramycin
