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Acute adrenal insufficiency

Disease definition

Acute adrenal insufficiency (AAI) is a rare but severe condition caused by a sudden defective production of adrenal steroids (cortisol and aldosterone). It represents an emergency, thus the rapid recognition and prompt therapy are critical for survival even before the diagnosis is made.

ORPHA:95409

  • Synonym(s):
    • Acute adrenal failure
    • Acute adrenocortical insufficiency
    • Addisonian crisis
    • Adrenal crisis
    • Adrenocortical crisis
  • Prevalence: Unknown
  • Inheritance: Autosomal recessive or X-linked dominant or Not applicable 
  • Age of onset: All ages
  • ICD-10: E27.2
  • OMIM: -
  • UMLS: C0151467
  • MeSH: -
  • GARD: -
  • MedDRA: -

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