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Diagnosis of acute myeloblastic leukemia (fusion genes and rearrangements: RUNX1-RUNX1T1 (AML1-ETO), CBFB-MYH11, PML-RARA, MLLT3-MLL (AF9-MLL), DEK-NUP214 (DEK-CAN), RPN1-EVI1, RBM15-MKL1, MLL, RUNX1-EVI1; aberrations of chromosom 17 (17p13 / TP53), 5/5q, 7/7q; mutation analysis of FLT-TKD, WT1, C- KIT, N- RAS, GATA1, GATA2, RUNX1 (AML1), CEBPA)

Despite our efforts to ensure that data is up to date, this activity has not been validated since 13/06/2017
  • Institut fr Humangenetik
  • Zentrum Pathologie, Forensik und Genetik
  • Medizinische Hochschule Hannover
  • Carl-Neuberg-Str. 1
  • 30625 HANNOVER
  • GERMANY
  • Director of laboratory : Pr Brigitte SCHLEGELBERGER
  • More information
  • Phone : 49 (0)511 532 4520
  • Additional Phone : -
  • Fax : 49 (0)511 532 4521
  • Website
  • Contact
Last update: June 2017

Responsible of diagnostic test

Purpose(s)

Post-natal diagnosis
Somatic genetics

Technical procedure(s)

Molecular genetics
Targeted mutation analysis
PCR based techniques
Sequence analysis: entire coding region
Sanger sequencing
Cytogenetics
Detection of microdeletions/microduplications
FISH
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