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APP - amyloid beta precursor protein
- Synonym(s) : alpha-sAPP, peptidase nexin-II
- Previous symbols and names : AD1, Alzheimer disease, amyloid beta (A4) precursor protein
- Type : gene with protein product
- Chromosomal location : 21q21.3
- OMIM: 104760
- HGNC: 620
- UniProtKB: P05067
- Genatlas: APP
- GenCC: APP
- Ensembl: ENSG00000142192
- IUPHAR-DB: -
- Reactome: P05067
- LOVD: APP
Diseases list
- Disease-causing germline mutation(s) in ABetaA21G amyloidosis
ORPHA:324718 
- Disease-causing germline mutation(s) in ABeta amyloidosis, Arctic type
ORPHA:324723 - Disease-causing germline mutation(s) in ABeta amyloidosis, Dutch type
ORPHA:100006 - Disease-causing germline mutation(s) in ABeta amyloidosis, Iowa type
ORPHA:324708 - Disease-causing germline mutation(s) in ABeta amyloidosis, Italian type
ORPHA:324713 - Disease-causing germline mutation(s) in ABetaL34V amyloidosis
ORPHA:324703 - Disease-causing germline mutation(s) in Early-onset autosomal dominant Alzheimer disease
ORPHA:1020
: AssessedAdditional information
Patient-centred resources for this gene
Research activities on this gene
Specialised Social Services
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