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C3 - complement C3
- Synonym(s) : ARMD9, C3a, C3a anaphylatoxin, C3b, complement component C3a, complement component C3b, CPAMD1, prepro-C3
- Previous symbols and names : complement component 3
- Type : gene with protein product
- Chromosomal location : 19p13.3
- OMIM: 120700
- HGNC: 1318
- UniProtKB: P01024
- Genatlas: C3
- Ensembl: ENSG00000125730
- IUPHAR-DB: -
- Reactome: P01024
- LOVD: C3
Diseases list
- Disease-causing germline mutation(s) in Atypical hemolytic uremic syndrome with complement gene abnormality
ORPHA:544472 
- Disease-causing germline mutation(s) (loss of function) in Complement component 3 deficiency
ORPHA:280133 - Major susceptibility factor in NON RARE IN EUROPE: Age-related macular degeneration
ORPHA:279
: AssessedGene included in a panel of genes performed as part of a diagnostic test
Additional information
Patient-centred resources for this gene
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