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TBK1 - TANK binding kinase 1

Synonym(s) : NAK
Previous symbols and names : TANK-binding kinase 1
Type : gene with protein product
Chromosomal location : 12q14.2
OMIM: 604834
HGNC: 11584
UniProtKB: Q9UHD2
Genatlas: TBK1
GenCC: TBK1
Ensembl: ENSG00000183735
IUPHAR-DB: 2237
Reactome: Q9UHD2
LOVD: TBK1

Diseases list

Disease-causing germline mutation(s) (loss of function) in Frontotemporal dementia with motor neuron disease ORPHA:275872
Major susceptibility factor in Amyotrophic lateral sclerosis ORPHA:803
Major susceptibility factor in Herpes simplex virus encephalitis ORPHA:1930

: Assessed

Additional information

Patient-centred resources for this gene

Diagnostic tests (43)

Research activities on this gene

Specialised Social Services

Eurordis directory

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