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KRAS - KRAS proto-oncogene, GTPase
- Synonym(s) : KRAS1, K-Ras4B
- Previous symbols and names : KRAS2, Kirsten rat sarcoma viral oncogene homolog, V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
- Type : gene with protein product
- Chromosomal location : 12p12.1
- OMIM: 190070
- HGNC: 6407
- UniProtKB: P01116
- Genatlas: KRAS
- GenCC: KRAS
- Ensembl: ENSG00000133703
- IUPHAR-DB: 2824
- Reactome: P01116
- LOVD: KRAS
Diseases list
- Disease-causing germline mutation(s) in Noonan syndrome
ORPHA:648 - Disease-causing germline mutation(s) (gain of function) in Cardiofaciocutaneous syndrome
ORPHA:1340 - Disease-causing somatic mutation(s) in Differentiated thyroid carcinoma
ORPHA:146 - Disease-causing somatic mutation(s) in Juvenile myelomonocytic leukemia
ORPHA:86834 - Disease-causing somatic mutation(s) in Linear nevus sebaceus syndrome
ORPHA:2612 - Disease-causing somatic mutation(s) in Pilomyxoid astrocytoma
ORPHA:251615 - Disease-causing somatic mutation(s) in RAS-associated autoimmune leukoproliferative disease
ORPHA:268114 - Disease-causing somatic mutation(s) in Toriello-Lacassie-Droste syndrome
ORPHA:3339 - Major susceptibility factor in Familial pancreatic carcinoma
ORPHA:1333 - Biomarker tested in Lynch syndrome
ORPHA:144 - Candidate gene tested in Encephalocraniocutaneous lipomatosis
ORPHA:2396

Additional information
Patient-centred resources for this gene
Research activities on this gene
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