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LIG4 - DNA ligase 4
- Synonym(s) : DNA joinase, DNA repair enzyme, polydeoxyribonucleotide synthase [ATP] 4, polynucleotide ligase, sealase
- Previous symbols and names : ligase IV, DNA, ATP-dependent
- Type : gene with protein product
- Chromosomal location : 13q33.3
- OMIM: 601837
- HGNC: 6601
- UniProtKB: P49917
- Genatlas: LIG4
- GenCC: LIG4
- Ensembl: ENSG00000174405
- IUPHAR-DB: -
- Reactome: P49917
- LOVD: LIG4
Diseases list
- Disease-causing germline mutation(s) in Dubowitz syndrome
ORPHA:235 
- Disease-causing germline mutation(s) in LIG4 syndrome
ORPHA:99812 - Disease-causing germline mutation(s) in Omenn syndrome
ORPHA:39041
: AssessedAdditional information
Patient-centred resources for this gene
Research activities on this gene
Specialised Social Services
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