Search for a gene
MRE11 - MRE11 homolog, double strand break repair nuclease
- Synonym(s) : ATLD, AT-like disease
- Previous symbols and names : MRE11 homolog A, double strand break repair nuclease, MRE11 meiotic recombination 11 homolog A (S. cerevisiae), MRE11A
- Type : gene with protein product
- Chromosomal location : 11q21
- OMIM: 600814
- HGNC: 7230
- UniProtKB: P49959
- Genatlas: MRE11A
- GenCC: MRE11A
- Ensembl: ENSG00000020922
- IUPHAR-DB: -
- Reactome: P49959
- LOVD: MRE11
Diseases list
- Disease-causing germline mutation(s) in Ataxia-telangiectasia-like disorder
ORPHA:251347 
- Disease-causing germline mutation(s) (loss of function) in Nijmegen breakage syndrome-like disorder
ORPHA:240760 - Candidate gene tested in Hereditary breast and/or ovarian cancer syndrome
ORPHA:145
: AssessedAdditional information
Patient-centred resources for this gene
Research activities on this gene
Specialised Social Services
The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.
Orphanet is part of the Gene Curation Coalition, a global effort to harmonise gene-level resources.