Search for a gene
NRAS - NRAS proto-oncogene, GTPase
- Synonym(s) : N-ras
- Previous symbols and names : neuroblastoma RAS viral (v-ras) oncogene homolog, neuroblastoma RAS viral oncogene homolog
- Type : gene with protein product
- Chromosomal location : 1p13.2
- OMIM: 164790
- HGNC: 7989
- UniProtKB: P01111
- Genatlas: NRAS
- GenCC: NRAS
- Ensembl: ENSG00000213281
- IUPHAR-DB: 2823
- Reactome: P01111
- LOVD: NRAS
Diseases list
- Disease-causing germline mutation(s) in Noonan syndrome
ORPHA:648 
- Disease-causing somatic mutation(s) in Differentiated thyroid carcinoma
ORPHA:146 - Disease-causing somatic mutation(s) in Juvenile myelomonocytic leukemia
ORPHA:86834 - Disease-causing somatic mutation(s) in Langerhans cell histiocytosis
ORPHA:389 - Disease-causing somatic mutation(s) in Large congenital melanocytic nevus
ORPHA:626 - Disease-causing somatic mutation(s) in NON RARE IN EUROPE: Melanoma
ORPHA:411533 - Disease-causing somatic mutation(s) in RAS-associated autoimmune leukoproliferative disease
ORPHA:268114 - Candidate gene tested in Linear nevus sebaceus syndrome
ORPHA:2612
: AssessedAdditional information
Patient-centred resources for this gene
Research activities on this gene
Specialised Social Services
The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.
Orphanet is part of the Gene Curation Coalition, a global effort to harmonise gene-level resources.