Orphanet: tet methylcytosine dioxygenase 2

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TET2 - tet methylcytosine dioxygenase 2

Synonym(s) : FLJ20032
Previous symbols and names : KIAA1546, tet oncogene family member 2
Type : gene with protein product
Chromosomal location : 4q24
OMIM: 612839
HGNC: 25941
UniProtKB: Q6N021
Genatlas: TET2
Ensembl: ENSG00000168769
IUPHAR-DB: -
Reactome: Q6N021
LOVD: TET2

Diseases list

Disease-causing somatic mutation(s) in Acquired idiopathic sideroblastic anemia ORPHA:75564
Disease-causing somatic mutation(s) in Acute myeloid leukaemia with myelodysplasia-related features ORPHA:86845
Disease-causing somatic mutation(s) in Aggressive systemic mastocytosis ORPHA:98850
Disease-causing somatic mutation(s) in Polycythemia vera ORPHA:729
Disease-causing somatic mutation(s) in Primary myelofibrosis ORPHA:824
Disease-causing somatic mutation(s) in Refractory anemia ORPHA:98826
Disease-causing somatic mutation(s) in Refractory anemia with excess blasts ORPHA:86839
Disease-causing somatic mutation(s) in Systemic mastocytosis with associated hematologic neoplasm ORPHA:98849
Biomarker tested in Essential thrombocythemia ORPHA:3318

: Assessed

Gene included in a panel of genes performed as part of a diagnostic test

Additional information

Patient-centred resources for this gene

Diagnostic tests (40)

Research activities on this gene

Specialised Social Services

Eurordis directory

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