Clinical Signs and Symptoms
ORPHA:39812 Graft versus host disease
The phenotypic description of this disease is based on an analysis of the biomedical literature and uses the terms of the Human Phenotype Ontology (HPO). Phenotypic abnormalities are presented by order of frequency of occurrence in the patient population, then by alphabetical order inside each frequency group.
- Inflammatory abnormality of the skin HP:0011123
Very frequent
- Chronic hepatitis HP:0200123
- Diarrhea HP:0002014
- Elevated hepatic transaminase HP:0002910
- Maculopapular exanthema HP:0040186
- Oral ulcer HP:0000155
- Recurrent infections HP:0002719
- Skin erosion HP:0200041
- Stomatitis HP:0010280
Frequent
- Abdominal pain HP:0002027
- Acute hepatitis HP:0200119
- Arthritis HP:0001369
- Cutaneous sclerotic plaque HP:0031359
- Elevated alkaline phosphatase HP:0003155
- Fasciitis HP:0100537
- Gastrointestinal inflammation HP:0004386
- Hemophagocytosis HP:0012156
- Hepatosplenomegaly HP:0001433
- Hyperbilirubinemia HP:0002904
- Inflammatory abnormality of the eye HP:0100533
- Irritability HP:0000737
- Jaundice HP:0000952
- Lichenoid skin lesion HP:0031452
- Limited elbow movement HP:0002996
- Limited shoulder movement HP:0006467
- Myositis HP:0100614
- Nausea HP:0002018
- Pneumonia HP:0002090
- Pulmonary infiltrates HP:0002113
- Recurrent gastroenteritis HP:0031123
- Scaling skin HP:0040189
- Skeletal muscle atrophy HP:0003202
- Tachycardia HP:0001649
- Vomiting HP:0002013
Occasional
- Decreased lacrimation HP:0000633
- Dupuytren contracture HP:0005679
- Failure to thrive HP:0001508
- Lipodystrophy HP:0009125
- Lymphadenopathy HP:0002716
- Stiff interphalangeal joints HP:0005198
- Trismus HP:0000211
Rare
Additional information
Further information
Specialised Social Services
Warning
The information provided is based on published scientific articles.
The information provided is estimated for the entire population of patients in routine care. Some phenotypic abnormalities reported here may occur individually with a variable temporality or severity, while others, not listed, may still be encountered. Phenotypic annotations are not yet available for all rare diseases; the annotation process is ongoing.
The information contained in Orphanet is regularly updated. It is possible that discoveries have been made since the last update and have not yet been incorporated.
Professionals are encouraged to always consult the latest scientific publications before making a decision based on the information provided. The information contained in Orphanet is not intended to replace the services of a healthcare professional. Orphanet cannot be held responsible for the deleterious, truncated or erroneous use of any information found in the Orphanet database.