Clinical Signs and Symptoms
ORPHA:91349 Non-functioning pituitary adenoma
The phenotypic description of this disease is based on an analysis of the biomedical literature and uses the terms of the Human Phenotype Ontology (HPO). Phenotypic abnormalities are presented by order of frequency of occurrence in the patient population, then by alphabetical order inside each frequency group.
- Abnormal muscle physiology HP:0011804
- Abnormality of hair density HP:0011357
- Abnormality of the menstrual cycle HP:0000140
- Abnormality of the pituitary gland HP:0012503
- Adrenal insufficiency HP:0000846
- Adrenocorticotropic hormone deficiency HP:0011748
- Adrenocorticotropin deficient adrenal insufficiency HP:0011735
- Anemia of inadequate production HP:0010972
- Anterior hypopituitarism HP:0000830
- Central adrenal insufficiency HP:0011734
- Decreased circulating ACTH level HP:0002920
- Decreased female libido HP:0030018
- Decreased fertility in females HP:0000868
- Decreased fertility in males HP:0012041
- Easy fatigability HP:0003388
- Erectile dysfunction HP:0100639
- Fatigue HP:0012378
- Female hypogonadism HP:0000134
- Growth hormone deficiency HP:0000824
- Headache HP:0002315
- Hypogonadism HP:0000135
- Hypogonadotrophic hypogonadism HP:0000044
- Hypopituitarism HP:0040075
- Hypotension HP:0002615
- Impotence HP:0000802
- Increased circulating gonadotropin level HP:0000837
- Increased intraabdominal fat HP:0008993
- Irregular menstruation HP:0000858
- Low gonadotropins (secondary hypogonadism) HP:0003335
- Male hypogonadism HP:0000026
- Nausea and vomiting HP:0002017
- Pallor HP:0000980
- Pituitary hypothyroidism HP:0008245
- Progressive visual loss HP:0000529
- Secondary growth hormone deficiency HP:0008240
- Vomiting HP:0002013
Frequent
- Bitemporal hemianopia HP:0030521
- Blindness HP:0000618
- Central diabetes insipidus HP:0000863
- Cranial nerve VI palsy HP:0006897
- Cranial nerve paralysis HP:0006824
- Diabetes insipidus HP:0000873
- Diplopia HP:0000651
- Fourth cranial nerve palsy HP:0007011
- Hemianopia HP:0012377
- Heteronymous hemianopia HP:0030517
- Increased serum testosterone level HP:0030088
- Internal ophthalmoplegia HP:0007942
- Macroorchidism HP:0000053
- Macroorchidism, postpubertal HP:0002050
- Oculomotor nerve palsy HP:0012246
- Panhypopituitarism HP:0000871
- Ptosis HP:0000508
- Reduced circulating prolactin concentration HP:0008202
- Seizures HP:0001250
- Sudden loss of visual acuity HP:0001117
- Vertigo HP:0002321
Occasional
Additional information
Further information
Specialised Social Services
Warning
The information provided is based on published scientific articles.
The information provided is estimated for the entire population of patients in routine care. Some phenotypic abnormalities reported here may occur individually with a variable temporality or severity, while others, not listed, may still be encountered. Phenotypic annotations are not yet available for all rare diseases; the annotation process is ongoing.
The information contained in Orphanet is regularly updated. It is possible that discoveries have been made since the last update and have not yet been incorporated.
Professionals are encouraged to always consult the latest scientific publications before making a decision based on the information provided. The information contained in Orphanet is not intended to replace the services of a healthcare professional. Orphanet cannot be held responsible for the deleterious, truncated or erroneous use of any information found in the Orphanet database.