Clinical Signs and Symptoms
ORPHA:97280 Glucagonoma
The phenotypic description of this disease is based on an analysis of the biomedical literature and uses the terms of the Human Phenotype Ontology (HPO). Phenotypic abnormalities are presented by order of frequency of occurrence in the patient population, then by alphabetical order inside each frequency group.
- Neoplasm of the pancreas HP:0002894
Very frequent
- Abnormal blistering of the skin HP:0008066
- Acanthocytosis HP:0001927
- Anorexia HP:0002039
- Chronic fatigue HP:0012432
- Constipation HP:0002019
- Diabetes mellitus HP:0000819
- Diarrhea HP:0002014
- Episodic abdominal pain HP:0002574
- Glossitis HP:0000206
- Hepatomegaly HP:0002240
- Nausea and vomiting HP:0002017
- Necrolytic migratory erythema HP:0031181
- Normochromic anemia HP:0001895
- Poor appetite HP:0004396
- Pruritus HP:0000989
- Skin rash HP:0000988
- Stomatitis HP:0010280
- Weight loss HP:0001824
Frequent
- Abnormal gastrointestinal motility HP:0030895
- Abnormality of abdomen morphology HP:0001438
- Ascites HP:0001541
- Depressivity HP:0000716
- Extrahepatic cholestasis HP:0012334
- Gastrointestinal hemorrhage HP:0002239
- Intermittent jaundice HP:0001046
- Intestinal obstruction HP:0005214
- Intrahepatic cholestasis HP:0001406
- Lack of bowel sounds HP:0030145
- Steatorrhea HP:0002570
- Thromboembolism HP:0001907
Occasional
- Abnormality of the thyroid gland HP:0000820
- Adrenocortical adenoma HP:0008256
- Growth hormone excess HP:0000845
- Hypercalcemia HP:0003072
- Hypercortisolism HP:0001578
- Increased circulating gonadotropin level HP:0000837
- Increased circulating prolactin concentration HP:0000870
- Parathyroid adenoma HP:0002897
- Pituitary adenoma HP:0002893
- Primary hyperparathyroidism HP:0008200
- Subcutaneous lipoma HP:0001031
Rare
Additional information
Further information
Specialised Social Services
Warning
The information provided is based on published scientific articles.
The information provided is estimated for the entire population of patients in routine care. Some phenotypic abnormalities reported here may occur individually with a variable temporality or severity, while others, not listed, may still be encountered. Phenotypic annotations are not yet available for all rare diseases; the annotation process is ongoing.
The information contained in Orphanet is regularly updated. It is possible that discoveries have been made since the last update and have not yet been incorporated.
Professionals are encouraged to always consult the latest scientific publications before making a decision based on the information provided. The information contained in Orphanet is not intended to replace the services of a healthcare professional. Orphanet cannot be held responsible for the deleterious, truncated or erroneous use of any information found in the Orphanet database.