Clinical Signs and Symptoms
ORPHA:168984 CLAPO syndrome
The phenotypic description of this disease is based on an analysis of the biomedical literature and uses the terms of the Human Phenotype Ontology (HPO). Phenotypic abnormalities are presented by order of frequency of occurrence in the patient population, then by alphabetical order inside each frequency group.
- Capillary hemangioma HP:0005306
- Capillary malformation of the lip HP:0031487
Always present
- Hemihypertrophy HP:0001528
- Lymphangioma HP:0100764
- Nevus flammeus HP:0001052
- Overgrowth HP:0001548
Very frequent
- Asymmetric growth HP:0100555
- Facial asymmetry HP:0000324
- Failure to thrive HP:0001508
- Hemihypertrophy of lower limb HP:0100553
- Hemihypertrophy of upper limb HP:0100554
- Lymphedema HP:0001004
- Macrodactyly HP:0004099
- Varicose veins HP:0002619
- Venous malformation HP:0012721
Frequent
- Narrow chest HP:0000774
- Pectus excavatum HP:0000767
- Tall stature HP:0000098
Occasional
- Ganglioneuroma HP:0003005
Rare
- Intellectual disability HP:0001249
Additional information
Further information
Specialised Social Services
Warning
The information provided is based on published scientific articles.
The information provided is estimated for the entire population of patients in routine care. Some phenotypic abnormalities reported here may occur individually with a variable temporality or severity, while others, not listed, may still be encountered. Phenotypic annotations are not yet available for all rare diseases; the annotation process is ongoing.
The information contained in Orphanet is regularly updated. It is possible that discoveries have been made since the last update and have not yet been incorporated.
Professionals are encouraged to always consult the latest scientific publications before making a decision based on the information provided. The information contained in Orphanet is not intended to replace the services of a healthcare professional. Orphanet cannot be held responsible for the deleterious, truncated or erroneous use of any information found in the Orphanet database.