Clinical Signs and Symptoms
ORPHA:363549 Acute encephalopathy with biphasic seizures and late reduced diffusion
The phenotypic description of this disease is based on an analysis of the biomedical literature and uses the terms of the Human Phenotype Ontology (HPO). Phenotypic abnormalities are presented by order of frequency of occurrence in the patient population, then by alphabetical order inside each frequency group.
- Bilateral tonic-clonic seizure HP:0002069
Very frequent
- Abnormal metabolic brain imaging by MRS HP:0012705
- Complex febrile seizure HP:0011172
- Hypointensity of cerebral white matter on MRI HP:0007103
- Increased circulating procalcitonin level HP:0032308
- Loss of consciousness HP:0007185
- Seizure cluster HP:0033349
- Seizure precipitated by febrile infection HP:0032894
- Severe viral infection HP:0031691
Frequent
- Status epilepticus without prominent motor symptoms HP:0031475
- Uncontrolled eye movements HP:0007738
Occasional
- Takotsubo cardiomyopathy HP:0011665
Rare
Additional information
Further information
Specialised Social Services
Warning
The information provided is based on published scientific articles.
The information provided is estimated for the entire population of patients in routine care. Some phenotypic abnormalities reported here may occur individually with a variable temporality or severity, while others, not listed, may still be encountered. Phenotypic annotations are not yet available for all rare diseases; the annotation process is ongoing.
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Professionals are encouraged to always consult the latest scientific publications before making a decision based on the information provided. The information contained in Orphanet is not intended to replace the services of a healthcare professional. Orphanet cannot be held responsible for the deleterious, truncated or erroneous use of any information found in the Orphanet database.