Clinical Signs and Symptoms
ORPHA:2518 Autosomal recessive chorioretinopathy-microcephaly syndrome
The phenotypic description of this disease is based on an analysis of the biomedical literature and uses the terms of the Human Phenotype Ontology (HPO). Phenotypic abnormalities are presented by order of frequency of occurrence in the patient population, then by alphabetical order inside each frequency group.
- Abnormality of retinal pigmentation HP:0007703
- Microcephaly HP:0000252
Very frequent
- Abnormal eyelash morphology HP:0000499
- Abnormality of neuronal migration HP:0002269
- Anteverted nares HP:0000463
- Aplasia/Hypoplasia of the cerebellum HP:0007360
- Biparietal narrowing HP:0004422
- Cerebral cortical atrophy HP:0002120
- Hypertonia HP:0001276
- Intellectual disability HP:0001249
- Intrauterine growth retardation HP:0001511
- Nystagmus HP:0000639
- Optic atrophy HP:0000648
- Pointed chin HP:0000307
- Protruding ear HP:0000411
- Scoliosis HP:0002650
- Seizures HP:0001250
- Short stature HP:0004322
- Sloping forehead HP:0000340
- Strabismus HP:0000486
- Visual impairment HP:0000505
- Wide nasal bridge HP:0000431
Frequent
Additional information
Further information
Specialised Social Services
Warning
The information provided is based on published scientific articles.
The information provided is estimated for the entire population of patients in routine care. Some phenotypic abnormalities reported here may occur individually with a variable temporality or severity, while others, not listed, may still be encountered. Phenotypic annotations are not yet available for all rare diseases; the annotation process is ongoing.
The information contained in Orphanet is regularly updated. It is possible that discoveries have been made since the last update and have not yet been incorporated.
Professionals are encouraged to always consult the latest scientific publications before making a decision based on the information provided. The information contained in Orphanet is not intended to replace the services of a healthcare professional. Orphanet cannot be held responsible for the deleterious, truncated or erroneous use of any information found in the Orphanet database.