Clinical Signs and Symptoms
ORPHA:1501 Adrenocortical carcinoma
The phenotypic description of this disease is based on an analysis of the biomedical literature and uses the terms of the Human Phenotype Ontology (HPO). Phenotypic abnormalities are presented by order of frequency of occurrence in the patient population, then by alphabetical order inside each frequency group.
- Adrenocortical carcinoma HP:0006744
Always present
- Abdominal pain HP:0002027
- Abnormal serum dehydroepiandrosterone level HP:0500022
- Abnormality of metabolism/homeostasis HP:0001939
- Abnormality of reproductive system physiology HP:0000080
- Adrenocorticotropic hormone deficiency HP:0011748
- Anxiety HP:0000739
- Diabetes mellitus HP:0000819
- Elevated serum 11-deoxycortisol HP:0025436
- Hyperaldosteronism HP:0000859
- Hyperhidrosis HP:0000975
- Hypertension HP:0000822
- Hypertrichosis HP:0000998
- Hypokalemia HP:0002900
- Increased body weight HP:0004324
- Increased circulating androgen concentration HP:0030348
- Increased circulating cortisol level HP:0003118
- Increased serum androstenedione HP:0025380
- Increased serum estradiol HP:0025134
- Increased urinary cortisol level HP:0012030
- Irritability HP:0000737
- Lung adenocarcinoma HP:0030078
- Muscle weakness HP:0001324
- Palpitations HP:0001962
- Panic attack HP:0025269
- Paradoxical increased cortisol secretion on dexamethasone suppression test HP:0003466
- Striae distensae HP:0001065
- Weight loss HP:0001824
Frequent
- Abnormality of urine homeostasis HP:0003110
Occasional
Additional information
Further information
Specialised Social Services
Warning
The information provided is based on published scientific articles.
The information provided is estimated for the entire population of patients in routine care. Some phenotypic abnormalities reported here may occur individually with a variable temporality or severity, while others, not listed, may still be encountered. Phenotypic annotations are not yet available for all rare diseases; the annotation process is ongoing.
The information contained in Orphanet is regularly updated. It is possible that discoveries have been made since the last update and have not yet been incorporated.
Professionals are encouraged to always consult the latest scientific publications before making a decision based on the information provided. The information contained in Orphanet is not intended to replace the services of a healthcare professional. Orphanet cannot be held responsible for the deleterious, truncated or erroneous use of any information found in the Orphanet database.